- Fought in the Spanish-American War of 1898. Later also fought in World War I.
- Was in three Oscar Best Picture nominees: The Broadway Melody (1929), Here Comes Mr. Jordan (1941) and The Bishop's Wife (1947), with the first of these being a winner in the category.
- Was seriously considered for the role of Hopalong Cassidy, which William Boyd made popular.
- His wife and son predeceased him. A grandson, Michael Gleason, survived.
- Vice-president for the Catholic Motion Picture Guild of America. The other vice-presidents (under president James Ryan) were John J. Gain, C.E. Sullivan and Johnny Hines (per the 1931 Motion Picture Almanac).
- Appeared in 17 films with his wife, Lucille Gleason.
- Father, with actress Lucile Gleason, of actor Russell Gleason.
- Based on both date of birth and age at time of appearance, he was the oldest actor or actress to appear on Leave It to Beaver (1957).
- Grandfather of Michael Lindsay.
- Father-in-law of Cynthia Lindsay.
- Son of actress Mina Gleason.
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