- (1999) Sings on the track "Slide Away" on the self-titled Michael Hutchence solo album.
- (1989) Wrote and produced the song, "She's a Mystery to Me", for Roy Orbison.
- (1989) Appears on Melissa Etheridge's Album "Brave and Crazy".
- (1993) Co-wrote "Miserere" with Zucchero, which has been covered by Luciano Pavarotti & Andrea Bocelli.
- (2001) Appears on Mick Jagger's solo album "Goddess in the Doorway".
- (2003) Appears on Daniel Lanois' Album "Shine".
- TV commercial with U2 for Apple iPod (2004)
- Public service announcement for The ONE Campaign [www.one.org] (2005)
- A member of the "Artists United Against Apartheid" charity project in 1985.
- Appeared as himself in a short student film titled "Sightings of Bono" (2000) after learning they were trying to find a look-a-like to play him.
- (2005) Sang a duet of the Peter Gabriel song "Don't Give Up" with Alicia Keys for the charity "Keep a Child Alive".
- Edited the British Independent newspaper (16 May 2006)
- Music video for Mary J. Blige: "One".
- 2000: Wrote liner notes for the Johnny Cash box set "Love, God, & Murder" alongside filmmaker Quentin Tarantino.
- (July 2007) Guest editor of Vanity Fair's "Africa Issue"
- (2003) Illustrated the children's book "Peter and the Wolf" for the Irish Hospice Foundation.
- (2011) Print advertisement (with wife Ali Hewson) for Louis Vuitton's EDUN baggage line (ethically made products founded by Ali Hewson and Bono) slogan: "Every journey began in Africa"
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