- Della was an ordained minister. She officiated at the wedding of Touched by an Angel (1994) co-star Roma Downey. She is the godmother of Downey's daughter, Reilly Marie.
- Composed the Touched by an Angel (1994) theme song "Walk With You".
- Was honored at Oprah Winfrey's Legends Ball ceremony along with 25 other African-American women. (2005)
- Suffered a stroke on the set of The Tonight Show (1962). [3 October 1979].
- Had four children: Deloresse Daniels Owens (1961-March 14, 2002, adopted), James, Franklin, and Dominique. Her daughter Deloreese was her adopted child whom she acquired from a family member unable to care for her. Owens died on March 14, 2002. It was never released whether she died from suicide or from complications stemming from pituitary disease leaving behind two children, ages 19 and 21.
- Best known by the public for her starring role as Tess on Touched by an Angel (1994).
- She collapsed on the set of Touched by an Angel (1994), and was hospitalized. (2000)
- Earned $50,000 an episode - increased from $40,000 - for Touched by an Angel (1994). (1997)
- Received a Grammy Award nomination for her album "Della". (1960)
- In 2007, she officiated for the second time--she is an ordained minister--at a wedding of her Touched by an Angel (1994) co-star Roma Downey, in which she married reality television show producer Mark Burnett.
- Her song, "Don't You Know?" reached the #2 spot on the Pop Charts and topped the R&B charts (1959), which were then called the "Hot R&B Sides". The song was adapted from Puccini's music for La Bohème; specifically, the aria Musetta's Waltz.
- In 1944, when she was 13, she was invited by legendary gospel singer, Mahalia Jackson, to attend a Southern Tour. Jackson was so impressed by the teenager's voice that she enlisted her for a summer tour, and Reese went on to tour with her for five summers.
- She was the first African-American actress to have hosted a talk show and the first African-American woman to have guest hosted The Tonight Show Starring Johnny Carson (1962).
- She was the first gospel singer ever to perform in Las Vegas, Nevada.
- Her oldest sister was 20, when Della was born, nobody lived with her, making Reese, the only child.
- The IRS Criminal Division began investigating the disappearance of nearly $2 million from vanishing church banking investments, as well as questionable/misappropriation of church funds and not paying church employees their earned wages at Understanding Principles for Better Living. (2014)
- Every Christmas when Reese was growing up, her mother baked her favorite cake, made her favorite dinner, and made crocheted items for her.
- A lyric-soprano.
- When Reese was a teenager, she also appeared at the Hotel Utah, in Salt Lake City. At that time, she was not allowed to stay there, because she was African-American. She had to both enter and exit through the service entrance.
- Her hobbies (over her long life) were: singing, watching movies, spending time with her family, reading the Bible, praying, swimming, cooking, traveling and playing games.
- Was the spokesperson for the International Dyslexia Association in the 1990s.
- Before she was a successful actress, she served as director for a young people's choir in church.
- In the mid-1980s, Reese formed the Gospel Group Brilliance with fellow singers O.C. Smith, Mary Clayton, Vermettya Royster, and Eric Strom. They released an album that earned her a Grammy Nomination in the Gospel Category, for the song "You Gave Me Love," in 1987.
- In 1953, she was the youngest performer ever to have the highest singing voice than anybody in jazz music.
- Before she was a successful actress, she was also a dental receptionist.
- Every weekend for 9 seasons, when doing Touched by an Angel (1994), Reese commuted from her Beverly Hills, California, house to Salt Lake City, Utah, to film the show.
- Had also dropped and shortened her name from Delloreese Patricia Early to Della Reese, knowing it was too big for one club's marquee.
- She was inducted into the Rhythm & Blues Music Hall of Fame. [12 June 2017].
- Upon her death, she was cremated, her ashes were given to her family.
- She was awarded a Star on The Hollywood Walk of Fame at 7060 Hollywood Boulevard, in Hollywood, California, on July 12, 1994.
- Graduated from Cass Technical High School, in Detroit, Michigan, in 1947, at only 15 years old, who was also the first in her family to graduate early.
- Had sold her $7.5 million dollar home in Beverly Hills, California, with plans to rebuild. [7 November 2014].
- Had Cherokee Native American ancestry.
- A movie buff.
- Her parents, Nellie (née Mitchelle) Early, was a cook, and Richard Thaddeus Early, was a steel worker, ladies' man, and gambler.
- Just before her The Royal Family (1991) co-star's, Redd Foxx's death, he stepped away from rehearsals during the scene where he didn't have any speaking lines. He did what most sitcom actors have the freedom to do in that situation: asked his stand-in to fill in while he did a quick "Entertainment Tonight" interview. Well, the reportedly power-hungry producer who had a history of giving Redd a hard time, according to Reese, didn't like that Redd used a stand-in, so he interrupted Redd's interview to have him join the rehearsal instead. When Redd found out that all the producer called him in rehearsal for was to walk across the stage, he was livid and didn't understand why the stand-in couldn't do the job that he was there to do anyway.
- Had attended Understanding Principles for Better Living Church, in Los Angeles, California, as a member, beginning in 1979, and later as an ordained minister, from 1986 until her death, late in 2017.
- At age 38, Reese relocated from Westchester, New York, to Beverly Hills, California, in 1969, to become an actress, while continue pursing a career as a singer.
- Before she was a successful actress, she used to work at a nightclub with all the unfamiliar and legendary singers in New York City.
- Lifelong friend of the late Robert H. Schuller. They were both part of the religious movement, The Church of Religious Science (now known as: Center For Spiritual Living) and also visited Schuller's former church, Crystal Cathedral (now Christ Cathedral).
- Had almost appeared in every episode of Touched by an Angel (1994), with the exception of 3.
- Childhood friend of: Marla Gibbs.
- Had guest-starred on The Ed Sullivan Show (1948) 17 times.
- Began her recording contract with RCA Records in 1957.
- Went to the same high school with Ellen Burstyn.
- Has a Golden Palm Star on the Palm Springs Walk of Stars. [26 April 2015].
- She began singing at only 6.
- Her church, Understanding Principles for Better Living Church (UP Church), was 33 miles north of Crystal Cathedral (now Christ Cathedral), founded by her pastoral friend Robert H. Schuller.
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