- Kyra and her husband, Kevin Bacon, lost an undisclosed amount of money in the Bernie Madoff scandal.
- When she and Kevin Bacon appeared on the PBS show "Finding Your Roots", they discovered that they are very distant cousins (ninth cousins once removed).
- She is the daughter of Patricia Ann (Rosenwald) and Henry Dwight Sedgwick. Her mother was Ashkenazi Jewish, and her ancestors had come from Germany to New York in the 1800s. Her father was born to a well-known Yankee family of English descent, with roots going back to Colonial America of the 1600s, predominantly in Massachusetts. Her middle name "Minturn" is from her paternal great-grandmother Sarah May Minturn.
- Attended Sarah Lawrence College before transferring to the University of Southern California, where she graduated with a theatre degree.
- Was three months pregnant with her son Travis Bacon when she completed filming on Born on the Fourth of July (1989). Returned to work after giving birth to Travis to begin filming Mr. & Mrs. Bridge (1990).
- First cousin once removed of actress Edie Sedgwick.
- Currently resides in Sharon, Connecticut with her husband and two children.
- Auditioned unsuccessfully for a role in Flashdance (1983).
- She studied drama at HB Studio in Greenwich Village in New York City.
- Made her big-screen acting debut in War and Love (1985) and her producing debut in Losing Chase (1996).
- She was awarded a Star on the Hollywood Walk of Fame for Television at 6356 Hollywood Boulevard in Hollywood, California on June 8, 2009.
- Received the 1988 Theatre World award for her stage portrayal of Muriel McComber in Eugene O'Neill's "Ah, Wilderness!".
- Both Kyra and her husband, Kevin Bacon, have starred in period movies which were set in, and primarily filmed in and around, Baltimore, Maryland. First, Kevin starred in Diner (1982) and 22 years later, Kyra starred in Something the Lord Made (2004).
- Older sister of actor Robert Sedgwick. Half-sister of jazz guitarist Mike Stern.
- Born on the same date as Kevin Dillon.
- Studied acting with Michael Howard at Michael Howard Studios in New York City.
- Was a guest at Sarah Jessica Parker's 40th birthday party.
- Sister-in-law of Michael Bacon and Betsy Bacon.
- Often confused with actresses Cameron Diaz and Gwyneth Paltrow.
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