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- Television pilot based on the film. Although the show wasn't picked up for the fall schedule, CBS did air the pilot in the summer of 1990.
- Doctor, Doctor chronicles the exploits of four doctors who formed the Northeast Medical Partners. After completing their Harvard medical schooling and residences they all got together and setup their own partnership in Providence, Rhode Island.
- Mike can't understand Deirdre's extremely negative reaction upon learning that her patient, "Wake Up Providence" host Hugh Persons, is HIV-positive... until she confesses her fear that she may also be infected.
- Mike's ex Jenna Lathrop has returned. She left the Duke and Mike falls quickly back under her spell. She invites Mike and the gang to her new photo exhibit. She gets Mike to sign the waiver but there is a compromising photo that he missed.
- Mike is named an eligible bachelor and pretty every single woman is coming on to him. And it causes problems for him with his girlfriend.
- During poker night, Abe can't ignore his dissolving marriage. The gang sets him up with a date.
- Mike is setting up the old college room for Abe and Gail's anniversary. It even includes a script. Gail is not happy and Abe sleeps on the couch. Mike tries to surreptitiously set up the couple with Leona for a counseling session.
- Grant wants changes to the clinic to increase billing and Mike gets out-voted. Mike institutes an outrageous outfit but it backfires.
- Abe is in the doghouse. His wife Gail is hiding a secret with Mike. Deirdre decides to go to the wild side and finds unwanted attention.
- Mike gets in way over his head when he saves the life of a beautiful award-winning photographer, and soon falls for her advances. Meanwhile, Abe endures Grant's medical advice when the partnership insurance physicals come due.
- Abe has recruited a reluctant Deirdre into a softball tournament. Mike takes Grant to a dinner with his estranged aunt Laura (Susan Sullivan). Then Laura and Grant start getting serious.
- Mike is helping his pregnant patient Alicia to find adoptive parents for her baby. Deirdre is angry that her married boyfriend Steve is cheating on her, not with his wife but with a new girlfriend.
- Abe and Gail need help. Mike is getting sued by a patient's niece.
- Grant is doing hand modeling. Mike injures Abe's son Justin in a hockey accident. Justin is forced to miss the championship game.
- Deirdre is going away for the weekend with wrong number Kevin. He turns out to be a rich guy and he invites the gang to ride his private plane. The problem is that Deirdre's bad luck with men continues.
- Abe is retaking his test. Mike is confronted on his TV show by the opposing lawyer. The lawsuit goes badly and he is visited by a ghost.
- Grant is offered membership to an exclusive golf club. He invites Abe and when he arrives they give him the cold shoulder. Abe tells Grant that they're racist but he points if they were why would they make him a member since he's Jewish.
- A mouse is loose in the clinic. Mike goes on a house-call to treat murder mystery writer Olivia Judd. He tells her about an undetectable poison and soon her husband is dead.
- Mike develops a hernia after doing an exercise demonstration with Pia on the morning TV show. He needs surgery but is afraid to get it.
- When a doctor appears on the show to peddle a new plan he invented. Mike says it's just a fad and not effective. But the producer who uses it, decides to side with the doctor and ousts Mike.
- College mate Peter Balcovske is coming for a visit. The gang recalls Mike's first encounter with Peter during an eventful study session.
- Mike fires the incompetent nurse. Unbeknownst to him, Grant hires Mike's visiting mother as the new nurse.
- Abe reluctantly allows Mike to babysit while he takes his wife out for their anniversary. He's not happy with what Mike teaches his kid.
- Grant begins an office romance wit the new receptionist who's half his age.
- Mike is trying to start his own practice and his mother is having a party for his book. There is a book review in Playboy.