Poznań Society of Friends of Learning

The Poznań Society of Friends of Learning (Polish: Poznańskie Towarzystwo Przyjaciół Nauk, PTPN) is a learned society in Poznań, Poland, established in 1857, of scholars and scientists in all branches of learning. It has been one of the largest and most important general learned organizations in Poland.

When founded in the 19th century, the Poznań Society was the chief Polish scientific and cultural organization in Prussian Poland, and until the creation of Kraków's Academy of Learning (Akademia Umiejętności) in 1871–73 it was the most important learned society in all the Polish lands. In addition to its learned activities, the Society collected and secured art works and Polish national mementos.

In 1919 the Poznań Society initiated the founding of Poznań University (Adam Mickiewicz University).

Presidents

PTPN18

Tyrosine-protein phosphatase non-receptor type 18 is an enzyme that in humans is encoded by the PTPN18 gene.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This gene was found to be expressed in brain, colon tissues, and several different tumor-derived cell lines. The biological function of this PTP has not yet been determined.

Interactions

PTPN18 has been shown to interact with PSTPIP1.

References

Further reading

PTPN7

Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene.

Function

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Interactions

PTPN7 has been shown to interact with MAPK3 and MAPK1.