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StatisticalMethod
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0
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1
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291
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Can we compare 3 different experimental conditions with DESeq2?
DESeq2
StatisticalMethod
updated 4 months ago by
swbarnes2
★ 1.4k • written 4 months ago by
Esteban
• 0
0
votes
0
replies
221
views
Job:
Post-Doc: Development of a new method to study the distribution of the effect sizes of QTL
StatisticalMethod
Evolution
QuantitativeTrailLocus
Genetics
JobPosting
4 months ago
pierre.devillemereuil
• 0
0
votes
3
replies
610
views
Differences in differential analysis methods for RNA-Seq
DESeq2
StatisticalMethod
Proteomics
DifferentialExpression
RNASeq
updated 5 months ago by
ATpoint
★ 4.5k • written 5 months ago by
james.zhang20
• 0
2
votes
2
replies
1.6k
views
DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2
medianofratiostransformation
StatisticalMethod
Normalization
dispersion
9 months ago
Linton
• 0
1
vote
2
replies
763
views
How to perform longitudinal analysis using EdgeR
StatisticalMethod
FoldChange
edgeR
RNASeq
9 months ago
Sabiha
▴ 20
2
votes
2
replies
634
views
DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression
DESeq2
RNASeqData
RNASeq
StatisticalMethod
10 months ago
Manthos
• 0
4
votes
2
replies
1.1k
views
DecideTest vs topTAGs in edgeR
RNAseq
StatisticalMethod
edgeR
updated 11 months ago by
Gordon Smyth
51k • written 11 months ago by
alvaroperona1
▴ 10
3
votes
2
replies
845
views
Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod
RNASeqData
edgeR
DESeq2
updated 15 months ago by
Gordon Smyth
51k • written 15 months ago by
CDSPARKS
▴ 10
2
votes
3
replies
2.5k
views
deseq2 normalization and statistical method
normalization
deseq2
StatisticalMethod
updated 18 months ago by
ATpoint
★ 4.5k • written 19 months ago by
SH
• 0
2
votes
4
replies
921
views
Model comparison in mean-dispersion trend in DESeq2
DESeq2
StatisticalMethod
19 months ago
Loïc
• 0
0
votes
2
replies
913
views
Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent
StatisticalMethod
edgeR
MultidimensionalScaling
Normalization
20 months ago
rcreswell01
• 0
1
vote
3
replies
1.2k
views
Limma-voom with inverse probability weights (similar to sample weights)
limma
limma-voom
StatisticalMethod
updated 20 months ago by
Gordon Smyth
51k • written 20 months ago by
jay
▴ 10
0
votes
1
reply
643
views
DESeq2 paired multifactor test
DESeq2
StatisticalMethod
updated 22 months ago by
Michael Love
42k • written 23 months ago by
ijvechetti
▴ 10
0
votes
0
replies
767
views
Job:
Academic position in Non-clinical Biostatistics
JobPosting
StatisticalMethod
23 months ago
Laurent Gatto
1.6k
1
vote
2
replies
1.2k
views
Limma adj.p.value the same for many different p.values
limmaGUI
limma
adj.p.value
StatisticalMethod
2.0 years ago
walkerrh95
• 0
0
votes
0
replies
1.1k
views
Job:
Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's
StatisticalMethod
Genetics
molecularQTL
FunctionalGenomics
2.1 years ago
gaow
• 0
0
votes
0
replies
663
views
Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
2.6 years ago
dong
▴ 10
2
votes
3
replies
4.2k
views
Differential gene expression and (adjusted) p-values
edgeR
StatisticalMethod
updated 2.5 years ago by
ruez.richard
• 0 • written 2.7 years ago by
tmms
• 0
6
votes
4
replies
1.2k
views
Limma prametrization
limm
MathematicalBiology
limmaGUI
StatisticalMethod
2.7 years ago
Giovanni
• 0
2
votes
7
replies
1.7k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR
StatisticalMethod
3.1 years ago
Field -Ye
• 0
0
votes
2
replies
1.6k
views
To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation
StatisticalMethod
3.3 years ago
Aneesha
• 0
0
votes
1
reply
866
views
DESeq2 Design matrix
StatisticalMethod
DESeq2
updated 3.4 years ago by
Michael Love
42k • written 3.4 years ago by
Saif
• 0
6
votes
6
replies
1.9k
views
limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics
limma
StatisticalMethod
updated 3.6 years ago by
Gordon Smyth
51k • written 3.6 years ago by
Steve
▴ 10
1
vote
3
replies
1.3k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod
DESeq2
phyloseq
updated 3.7 years ago by
Michael Love
42k • written 3.7 years ago by
zardbid
• 0
0
votes
0
replies
1.4k
views
Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network
StatisticalMethod
WGCNA
ExpressionData
3.8 years ago
jol.espinoz
▴ 40
0
votes
2
replies
833
views
p adjusted value not available
StatisticalMethod
DESeq2
updated 3.9 years ago by
Kevin Blighe
★ 4.0k • written 3.9 years ago by
marie
• 0
26 results • Page
1 of 1
Recent ...
Replies
Comment: How to reverse complement some elements of a DNAStringSet
by
Christine Jones
• 0
Fantastic, thank you
Comment: When running contrasts, does it use normalized read counts?
by
Katherine
• 0
Ok, so the comment I was given where they said DeSeq2 should be with normalized counts is incorrect. the ```normalized_counts``` variable …
Answer: How to reverse complement some elements of a DNAStringSet
by
James W. MacDonald
67k
You should always try the vectorized method first, rather than looping. ``` > myFasta[myFasta_rc] <- reverseComplement(myFasta[myFasta_…
Answer: When running contrasts, does it use normalized read counts?
by
James W. MacDonald
67k
A contrast is a comparison of two or more coefficients. When you run `nbiomWaldTest` you are fitting the GLM and estimating coefficients. T…
Comment: Too much data for Diffbind
by
Ou, Jianhong
★ 1.3k
Just in case if somebody still want to apply summits greater than 0 and got the same error, you can filter out the peaks with start positio…
Votes
Comment: featureCounts fails to load annotation file
Answer: How to reverse complement some elements of a DNAStringSet
Answer: KEGGgraph result difference
Answer: What should be the normalization protocol for RNA seq data for WGCNA?
What should be the normalization protocol for RNA seq data for WGCNA?
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James W. MacDonald
67k
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shepherl
4.0k
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Gordon Smyth
51k
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bioinformaticssrm2011
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sukeshinik5
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