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Primidolol

С Википедије, слободне енциклопедије
Primidolol
Nazivi
IUPAC naziv
1-[2-[[2-Hidroksi-3-(2-metilfenoksi)propil]amino]etil]-5-metilpirimidin-2,4-dion
Identifikacija
3D model (Jmol)
ChemSpider
KEGG[1]
UNII
  • CC1=CC=CC=C1OCC(CNCCN2C=C(C(=O)NC2=O)C)O
Svojstva
C17H23N3O4
Molarna masa 333,39 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Primidolol je antagonist beta adrenergičkog receptora.[4][5][6]

  1. ^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  2. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  3. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  4. ^ Saltvedt, E; Fauchald, P (1980). „Effect of single and twice daily doses of primidolol (UK-11,443) in hypertension”. Current Medical Research and Opinion. 6 (8): 528—33. PMID 6104564. doi:10.1185/03007998009109482. 
  5. ^ Augstein, J.; Cox, D. A.; Ham, A. L.; Leeming, P. R.; Snarey, M. (1973). „Beta-adrenoceptor blocking agents. 1. Cardioselective 1-aryloxy-3-(aryloxyalkylamino)propan-2-ols”. Journal of Medicinal Chemistry. 16 (11): 1245—1251. PMID 4147835. doi:10.1021/jm00269a007. 
  6. ^ DE 2238504, Augstein, Joachim; Cox, David Alexander & Ham, Allan Leslie, "Propanolaminderivate [Propanolamine derivates]", published 1973-02-22, assigned to Pfizer Corp.