Primidolol
Изглед
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Nazivi | |
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IUPAC naziv
1-[2-[[2-Hidroksi-3-(2-metilfenoksi)propil]amino]etil]-5-metilpirimidin-2,4-dion
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Identifikacija | |
3D model (Jmol)
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ChemSpider | |
KEGG[1] | |
UNII | |
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Svojstva | |
C17H23N3O4 | |
Molarna masa | 333,39 g·mol−1 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
Reference infokutije | |
Primidolol je antagonist beta adrenergičkog receptora.[4][5][6]
Reference
[уреди | уреди извор]- ^ Joanne Wixon; Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast. 17 (1): 48—55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ Saltvedt, E; Fauchald, P (1980). „Effect of single and twice daily doses of primidolol (UK-11,443) in hypertension”. Current Medical Research and Opinion. 6 (8): 528—33. PMID 6104564. doi:10.1185/03007998009109482.
- ^ Augstein, J.; Cox, D. A.; Ham, A. L.; Leeming, P. R.; Snarey, M. (1973). „Beta-adrenoceptor blocking agents. 1. Cardioselective 1-aryloxy-3-(aryloxyalkylamino)propan-2-ols”. Journal of Medicinal Chemistry. 16 (11): 1245—1251. PMID 4147835. doi:10.1021/jm00269a007.
- ^ DE 2238504, Augstein, Joachim; Cox, David Alexander & Ham, Allan Leslie, "Propanolaminderivate [Propanolamine derivates]", published 1973-02-22, assigned to Pfizer Corp.