LY-301,317 je agonist 5-HT1A receptora.[3] Studije su pokazale da ligandi 5-HT1A receptora modulišu katalepsiju izazvanu antipsihoticima.

LY-301,317
Nazivi
Preferisani IUPAC naziv
(4S)-6-(1,3-oxazol-5-yl)-N,N-dipropyl-1,3,4,5-tetrahydrobenzo[cd]indol-4-amine
Drugi nazivi
ly301317
Identifikacija
3D model (Jmol)
  • CCCN(CCC)C1CC2=CNC3=C2C(=C(C=C3)C4=CN=CO4)C1
Svojstva
C20H25N3O
Molarna masa 323,44 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Reference

уреди
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Eric P M Prinssen; Francis C Colpaert; Wouter Koek (2002-10-25). „5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy”. Eur J Pharmacol. 453 (2-3): 217—21. doi:10.1016/s0014-2999(02)02430-5.