Keepsake is an open-source Python library designed to provide version control for machine learning experiments and models. It enables users to automatically track code, hyperparameters, training data, model weights, metrics, and Python dependencies, ensuring that all aspects of the machine learning workflow are recorded and reproducible. Keepsake integrates seamlessly with existing workflows by requiring minimal code additions, allowing users to continue training as usual while Keepsake saves code and weights to Amazon S3 or Google Cloud Storage. This facilitates the retrieval of code and weights from any checkpoint, aiding in re-training or model deployment. Keepsake supports various machine learning frameworks, including TensorFlow, PyTorch, scikit-learn, and XGBoost, by saving files and dictionaries in a straightforward manner. It also offers features such as experiment comparison, enabling users to analyze differences in parameters, metrics, and dependencies across experiments.