LigPlot+

LigPlot+

EMBL-EBI
SILCS

SILCS

SilcsBio
+

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About

LigPlot+ is a successor to our original LIGPLOT program for the automatic generation of 2D ligand-protein interaction diagrams. It is run from an intuitive java interface that allows on-screen editing of the plots via mouse click-and-drag operations. In addition to the new interface, the program includes several major enhancements over the old version. When two or more ligand-protein complexes are sufficiently similar, LigPlot+ can automatically display their interaction diagrams either superposed or side by side. Any conserved interactions are highlighted. The LigPlot+ suite also now includes an update of the original DIMPLOT program for plotting protein-protein or domain-domain interactions. Users can flexibly select the interface of interest and DIMPLOT will then generate a diagram showing the residue-residue interactions across the interface. To assist in interpretation, the residues in one of the interfaces can be optionally displayed in sequence order.

About

The core of extensible programming is defining functions. Python allows mandatory and optional arguments, keyword arguments, and even arbitrary argument lists. Whether you're new to programming or an experienced developer, it's easy to learn and use Python. Python can be easy to pick up whether you're a first-time programmer or you're experienced with other languages. The following pages are a useful first step to get on your way to writing programs with Python! The community hosts conferences and meetups to collaborate on code, and much more. Python's documentation will help you along the way, and the mailing lists will keep you in touch. The Python Package Index (PyPI) hosts thousands of third-party modules for Python. Both Python's standard library and the community-contributed modules allow for endless possibilities.

About

Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. Site-Identification by Ligand Competitive Saturation (SILCS) generates 3D maps (FragMaps) of interaction patterns for chemical functional groups with your target molecule. SILCS reveals intricacies of dynamics and provides tools to optimize ligand scaffolds using qualitative and quantitative binding pockets insights allowing more rapid and effective drug design. SILCS uses multiple small molecule probes with various functional groups, explicit solvent modeling, and target molecule flexibility to perform protein target mapping. Visualize favorable interactions with the target macromolecule. Gain insights to design better ligands with optimally placed functional groups.

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Platforms Supported

Windows
Mac
Linux
Cloud
On-Premises
iPhone
iPad
Android
Chromebook

Audience

Labs and researchers interested in a solution to create and visualize ligand-protein interaction diagrams

Audience

Developers interested in a beautiful but advanced programming language

Audience

Laboratories searching for a dynamic molecule design software to create end-to-end drug design workflows

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

Support

Phone Support
24/7 Live Support
Online

API

Offers API

API

Offers API

API

Offers API

Screenshots and Videos

Screenshots and Videos

Screenshots and Videos

Pricing

No information available.
Free Version
Free Trial

Pricing

Free
Free Version
Free Trial

Pricing

No information available.
Free Version
Free Trial

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

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Reviews/Ratings

Overall 5.0 / 5
ease 5.0 / 5
features 5.0 / 5
design 5.0 / 5
support 5.0 / 5

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Training

Documentation
Webinars
Live Online
In Person

Company Information

EMBL-EBI
United Kingdom
www.ebi.ac.uk/thornton-srv/software/LigPlus/

Company Information

Python
Founded: 1991
www.python.org

Company Information

SilcsBio
Founded: 2012
United States
silcsbio.com/software/

Alternatives

SILCS

SILCS

SilcsBio

Alternatives

Alternatives

Aurora Drug Discovery

Aurora Drug Discovery

Aurora Fine Chemicals
3decision

3decision

Discngine
3decision

3decision

Discngine
Aurora Drug Discovery

Aurora Drug Discovery

Aurora Fine Chemicals
LigPlot+

LigPlot+

EMBL-EBI
BioNeMo

BioNeMo

NVIDIA

Categories

Categories

Categories

Integrations

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Activeeon ProActive
Agentplace
Arm MAP
AutoRest
Bika.ai
Claude Opus 3
Claude Opus 4.5
Comet
Doc Converter Pro
Favtutor AI Code Generator
JetBrains Datalore
Lapce
Llama 3.2
ML Console
Qwiet AI
Seaborn
ToothPicker
Visplore
jEdit

Integrations

302.AI
Activeeon ProActive
Agentplace
Arm MAP
AutoRest
Bika.ai
Claude Opus 3
Claude Opus 4.5
Comet
Doc Converter Pro
Favtutor AI Code Generator
JetBrains Datalore
Lapce
Llama 3.2
ML Console
Qwiet AI
Seaborn
ToothPicker
Visplore
jEdit

Integrations

302.AI
Activeeon ProActive
Agentplace
Arm MAP
AutoRest
Bika.ai
Claude Opus 3
Claude Opus 4.5
Comet
Doc Converter Pro
Favtutor AI Code Generator
JetBrains Datalore
Lapce
Llama 3.2
ML Console
Qwiet AI
Seaborn
ToothPicker
Visplore
jEdit
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