Cython vs. D vs. IronPython vs. Python Comparison Chart

Cython is an optimizing static compiler for both the Python programming language and the extended Cython programming language (based on Pyrex). It makes writing C extensions for Python as easy as Python itself. Cython gives you the combined power of Python and C to let you write Python code that calls back and forth from and to C or C++ code natively at any point. Easily tune readable Python code into plain C performance by adding static type declarations, also in Python syntax. Use combined source code level debugging to find bugs in your Python, Cython, and C code. Interact efficiently with large data sets, e.g. using multi-dimensional NumPy arrays. Quickly build your applications within the large, mature, and widely used CPython ecosystem. The Cython language is a superset of the Python language that additionally supports calling C functions and declaring C types on variables and class attributes.

IronPython is an open-source implementation of the Python programming language which is tightly integrated with .NET. IronPython can use .NET and Python libraries, and other .NET languages can use Python code just as easily. Experience a more interactive .NET and Python development experience with Python Tools for Visual Studio. IronPython is an excellent addition to .NET, providing Python developers with the power of the .NET. Existing .NET developers can also use IronPython as a fast and expressive scripting language for embedding, testing, or writing a new application from scratch. The CLR is a great platform for creating programming languages, and the DLR makes it all the better for dynamic languages. Also, the .NET (base class library, presentation foundation, etc.) gives developers an amazing amount of functionality and power. IronPython uses Python syntax and standard libraries and so your Python code will need to be updated accordingly.