Fitepsin
Fitepsin (EC 3.4.23.40, Phytepsin) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fitepsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.40 | ||||||||
| CAS broj | 219715-98-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Postoji preferencija za hidrofobne ostatke Phe, Val, Ile, Leu, i Ala u P1 i P1', ali se takođe razlažu -Phe-Asp- i -Asp-Asp- veze u 2S albuminu iz biljnog semena
Ovaj enzim je pristan u zrnima ječma.
Reference
uredi- ↑ Runeberg-Roos, P., Törmäkangas, K. and Östman, A. (1991). „Primary structure of a barley-grain aspartic proteinase. A plant aspartic proteinase resembling mammalian cathepsin D”. Eur. J. Biochem. 202: 1021-1027. PMID 1722454.
- ↑ Kervinen, J., Sarkkinen, P., Kalkkinen, N., Mikola, L. and Saarma, M. (1993). „Hydrolytic specificity of the barley grain aspartic proteinase”. Phytochemistry 32: 799-803. PMID 7763475.
- ↑ Asakura, T., Watanabe, H., Abe, K. and Arai, S. (1995). „Rice aspartic proteinase, oryzasin, expressed during seed ripening and germination, has a gene organization distinct from those of animal and microbial aspartic proteinases”. Eur. J. Biochem. 232: 77-83. PMID 7556174.
- ↑ Kervinen, J., Törmäkangas, K., Runeberg-Roos, P., Guruprasad, K., Blundell, T. and Teeri, T.H. (1995). „Structure and possible function of aspartic proteinases in barley and other plants”. Adv. Exp. Med. Biol. 362: 241-254. PMID 8540324.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.