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Angeles Martin-Requero

Dr. Angeles Martin-Requero

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Dr. Ángeles Martín-Requero is the head of the “Cellular and Molecular basis of Alzheimer’s disease and other dementias” group at the Margarita Salas Center for Biological Research (CSIC), Madrid (Spain). Her expertise and research interests are related to the study of the molecular mechanisms involved in cell signaling under pathophysiological conditions. Specifically, her laboratory has been interested in the study of the mechanisms that cause neuronal death in neurodegenerative diseases, mainly focused on studying alterations in the control of the cell cycle and apoptosis, as well as damage to mitochondrial function, oxidative stress, and protein degradation. The general strategy used has been to define the mechanisms that cause neuronal death to identify potential therapeutic targets and biomarkers that could serve in both early diagnosis and follow-up with the disease in question. She was the mentor of 9 PhD theses, more than 10 master's theses, and many undergraduate students. She is also an expert evaluator of Spanish and international grants and fellowships; a reviewer of scientific journals from the neuroscience field; and the author of more than 70 publications, 2 patents in the pharmaceutical field, 6 book chapters, and numerous communications from scientific meetings

Research Keywords & Expertise

Amyotrophic lateral sc...
Frontotemporal lobar d...
TDP43 proteinopathies
Neurodegenerative dese...
Alzheimer ‘s disease

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Alzheimer ‘s disease
Amyotrophic lateral sclerosis (ALS)
Frontotemporal lobar degenerations
TDP43 proteinopathies

Short Biography

Dr. Ángeles Martín-Requero is the head of the “Cellular and Molecular basis of Alzheimer’s disease and other dementias” group at the Margarita Salas Center for Biological Research (CSIC), Madrid (Spain). Her expertise and research interests are related to the study of the molecular mechanisms involved in cell signaling under pathophysiological conditions. Specifically, her laboratory has been interested in the study of the mechanisms that cause neuronal death in neurodegenerative diseases, mainly focused on studying alterations in the control of the cell cycle and apoptosis, as well as damage to mitochondrial function, oxidative stress, and protein degradation. The general strategy used has been to define the mechanisms that cause neuronal death to identify potential therapeutic targets and biomarkers that could serve in both early diagnosis and follow-up with the disease in question. She was the mentor of 9 PhD theses, more than 10 master's theses, and many undergraduate students. She is also an expert evaluator of Spanish and international grants and fellowships; a reviewer of scientific journals from the neuroscience field; and the author of more than 70 publications, 2 patents in the pharmaceutical field, 6 book chapters, and numerous communications from scientific meetings