Fungal CNS infections in Africa: the neuroimmunology of cryptococcal meningitis

SH Mohamed, TK Nyazika, K Ssebambulidde… - Frontiers in …, 2022 - frontiersin.org
Cryptococcal meningitis (CM) is the leading cause of central nervous system (CNS) fungal
infections in humans, with the majority of cases reported from the African continent. This is …

Cryptococcosis in Africa: What the data tell us

C Ibe, CA Okoye, E Nweze, A Otu - Medical Mycology, 2023 - academic.oup.com
Cryptococcosis is a neglected tropical disease and the main cause of fungal-related deaths
in HIV-positive persons in Africa. It is an AIDS-defining illness that has almost surpassed …

Global Analyses of Multi-Locus Sequence Typing Data Reveal Geographic Differentiation, Hybridization, and Recombination in the Cryptococcus gattii Species …

M Hitchcock, J Xu - Journal of Fungi, 2023 - mdpi.com
Cryptococcus gattii species complex (CGSC) is a basidiomycete haploid yeast and globally
distributed mammalian pathogen. CGSC is comprised of six distinct lineages (VGI, VGII …

Exposure of Cryptococcus neoformans to Seven Commonly Used Agricultural Azole Fungicides Induces Resistance to Fluconazole as Well as Cross-Resistance to …

P Drakulovski, D Krasteva, V Bellet, S Randazzo… - Pathogens, 2023 - mdpi.com
Background: Cross-resistance to medical azoles by exposure to azole pesticides is well
documented for Aspergillus family fungi but is poorly evaluated for other environmental …

Cryptococcus neoformans VNII as the Main Cause of Cryptococcosis in Domestic Cats from Rio de Janeiro, Brazil

RS Reis, ICF Bonna, IMS Antonio, SA Pereira… - Journal of Fungi, 2021 - mdpi.com
Cryptococcosis is a systemic fungal disease acquired from contaminated environments with
propagules of the basidiomycetous yeasts of the Cryptococcus neoformans and C. gattii …

Epidemiology of Cryptococcus and cryptococcosis in Western Africa

CL Akaihe, EI Nweze - Mycoses, 2021 - Wiley Online Library
Cryptococcosis is a serious and sometimes fatal fungal disease caused by Cryptococcus
species. Worldwide, it is estimated to kill over 180 000 annually, with 75% of deaths …

Cryptococcus neoformans–astrocyte interactions: effect on fungal blood brain barrier disruption, brain invasion, and meningitis progression

YH Woo, LR Martinez - Critical reviews in microbiology, 2021 - Taylor & Francis
Cryptococcus neoformans is an opportunistic, neurotropic, and encapsulated fungus that
causes life-threatening cryptococcal meningitis (CM), especially in regions of the world …

Fluconazole Resistance and Virulence in In Vitro Induced-Fluconazole Resistant Strains and in Clinical Fluconazole Resistant Strain of Cryptococcus deuterogattii

S Bertout, L Laroche, F Roger, D Krasteva… - Pathogens, 2023 - mdpi.com
Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system,
caused by encapsulated yeast belonging to the Cryptococcus neoformans and …

Multilocus sequence typing of strains from the Cryptococcus gattii species complex from different continents

V Bellet, F Roger, D Krasteva, T Gouveia… - Mycoses, 2022 - Wiley Online Library
Abstract Background Cryptococcus neoformans and Cryptococcus gattii species complexes
are pathogens causing cryptococcal meningitis, a fungal infection that leads to death unless …

Cryptococcosis in HIV/AIDS patients in northern Brazil: clinical aspects, molecular types and isolation of agents from environmental samples associated with patients

MJ Alves, IS do Nascimento, KS Cruz… - Tropical Medicine & …, 2022 - Wiley Online Library
Objectives In the state of Amazonas, northern Brazil, cryptococcosis is endemic, with a
predominance of Cryptococcus neoformans in individuals with HIV/AIDS, and Cryptococcus …