[HTML][HTML] Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex

F Hagen, K Khayhan, B Theelen, A Kolecka… - Fungal genetics and …, 2015 - Elsevier
Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed
significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus …

Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Pulmonary cryptococcosis: a review of pathobiology and clinical aspects

F Setianingrum, R Rautemaa-Richardson… - Medical …, 2019 - academic.oup.com
Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …

[HTML][HTML] Associations between Cryptococcus Genotypes, Phenotypes, and Clinical Parameters of Human Disease: A Review

MC Montoya, PM Magwene, JR Perfect - Journal of Fungi, 2021 - mdpi.com
The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Cryptococcal Disease in Diverse Hosts

DB Meya, PR Williamson - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Cryptococcal Disease in Diverse Hosts Worldwide, cryptococcal meningitis kills
up to 180,000 persons annually and is the most common cause of nonviral meningitis in the …

Epidemiology of fungal infections in China

M Chen, Y Xu, N Hong, Y Yang, W Lei, L Du, J Zhao… - Frontiers of …, 2018 - Springer
With the increasing number of immunocompromised hosts, the epidemiological
characteristics of fungal infections have undergone enormous changes worldwide, including …

Importance of Resolving Fungal Nomenclature: the Case of Multiple Pathogenic Species in the Cryptococcus Genus

F Hagen, HT Lumbsch, V Arsic Arsenijevic, H Badali… - Msphere, 2017 - Am Soc Microbiol
Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and
Cryptococcus neoformans species complexes. After more than 15 years of molecular …

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level

J Rhodes, CA Desjardins, SM Sykes, MA Beale… - Genetics, 2017 - academic.oup.com
Cryptococcus neoformans var. grubii is the causative agent of cryptococcal meningitis, a
significant source of mortality in immunocompromised individuals, typically human …

[HTML][HTML] Genotypic diversity is associated with clinical outcome and phenotype in cryptococcal meningitis across Southern Africa

MA Beale, W Sabiiti, EJ Robertson… - PLoS neglected …, 2015 - journals.plos.org
Cryptococcal meningitis is a major cause of mortality throughout the developing world, yet
little is known about the genetic markers underlying Cryptococcal virulence and patient …

A population genomics approach to assessing the genetic basis of within-host microevolution underlying recurrent cryptococcal meningitis infection

J Rhodes, MA Beale, M Vanhove… - G3: Genes …, 2017 - academic.oup.com
Recurrence of meningitis due to Cryptococcus neoformans after treatment causes
substantial mortality in HIV/AIDS patients across sub-Saharan Africa. In order to determine …