Jason Chan, MD

Title(s)Assistant Professor, Radiation Oncology
SchoolSchool of Medicine
Address1600 Divisadero, #H1031
San Francisco CA 94115
Phone415-353-7175
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    Brown UniversityMD
    University of California, San FranciscoResidency

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    Dr. Jason Chan is a radiation oncologist who specializes in the treatment of head and neck, skull base, cutaneous, and thoracic malignancies. Dr. Chan received his undergraduate and medical degrees from Brown University. He completed his Internal Medicine internship at Kaiser Permanente San Francisco and his residency in Radiation Oncology at UCSF. He is an investigator in a number of translational studies and clinical trials in head and neck and lung cancers. His research interests include HPV-associated oropharyngeal cancer, nasopharyngeal cancer, lung, thyroid, and cutaneous malignancies. His clinical practice offers a wide range of treatment options for first time and repeat radiotherapy including Cyberknife radiosurgery and high-dose-rate brachytherapy.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Higher area deprivation index is associated with poorer local control and overall survival in non-metastatic nasopharyngeal carcinoma. Head Neck. 2024 06; 46(6):1468-1474. Malik NH, Montero M, Chen JJ, Sinha S, Yom SS, Chan JW. PMID: 38517113.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Evaluating the Hounsfield unit assignment and dose differences between CT-based standard and deep learning-based synthetic CT images for MRI-only radiation therapy of the head and neck. J Appl Clin Med Phys. 2024 Jan; 25(1):e14239. Singhrao K, Dugan CL, Calvin C, Pelayo L, Yom SS, Chan JW, Scholey JE, Singer L. PMID: 38128040; PMCID: PMC10795453.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Incidental findings and safety events from magnetic resonance imaging simulation for head and neck radiation treatment planning: A single institution experience. Tech Innov Patient Support Radiat Oncol. 2024 Mar; 29:100228. Massachi J, Singer L, Glastonbury C, Scholey J, Singhrao K, Calvin C, Yom SS, Chan JW. PMID: 38179087; PMCID: PMC10765101.
      View in: PubMed   Mentions:
    4. Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses. Nat Med. 2023 Dec; 29(12):3067-3076. Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC, Harmanci AS, Harmanci AO, Klisch TJ, Nguyen MP, Vasudevan HN, McCortney K, Yu TJ, Bhave V, Lam TC, Pu JK, Li LF, Leung GK, Chan JW, Perlow HK, Palmer JD, Haberler C, Berghoff AS, Preusser M, Nicolaides TP, Mawrin C, Agnihotri S, Resnick A, Rood BR, Chew J, Young JS, Boreta L, Braunstein SE, Schulte J, Butowski N, Santagata S, Spetzler D, Bush NAO, Villanueva-Meyer JE, Chandler JP, Solomon DA, Rogers CL, Pugh SL, Mehta MP, Sneed PK, Berger MS, Horbinski CM, McDermott MW, Perry A, Bi WL, Patel AJ, Sahm F, Magill ST, Raleigh DR. PMID: 37944590; PMCID: PMC11073469.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    5. Treatment Modality Impact on Patient-Reported Quality of Life in Human Papilloma Virus-Associated Oropharyngeal Carcinoma. Laryngoscope. 2024 Apr; 134(4):1687-1695. Plonowska-Hirschfeld KA, Gulati A, Stephens EM, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi A, Kang H, Ryan WR. PMID: 37767815.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. A prospective evaluation of neck and shoulder function following treatments of early-stage human papillomavirus-associated oropharynx cancer. Clin Otolaryngol. 2023 Sep; 48(5):756-765. Gulati A, Plonowska-Hirschfeld K, Stephens EM, Kansara S, Zebolsky AL, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi AP, Kang H, Ryan WR. PMID: 37212448.
      View in: PubMed   Mentions:    Fields:    
    7. Integrating CT-based radiomic model with clinical features improves long-term prognostication in high-risk prostate cancer. Front Oncol. 2023; 13:1060687. Ching JCF, Lam S, Lam CCH, Lui AOY, Kwong JCK, Lo AYH, Chan JWH, Cai J, Leung WS, Lee SWY. PMID: 37205204; PMCID: PMC10186349.
      View in: PubMed   Mentions: 2  
    8. Early-Stage Primary Lung Neuroendocrine Tumors Treated With Stereotactic Body Radiation Therapy: A Multi-Institution Experience. Int J Radiat Oncol Biol Phys. 2023 Jul 15; 116(4):849-857. Oliver DE, Laborde JM, Singh DP, Milano MT, Videtic GM, Williams GR, LaRiviere MJ, Chan JW, Peters GW, Decker RH, Samson P, Robinson CG, Breen WG, Owen D, Tian S, Higgins KA, Almeldin D, Jabbour SK, Wang F, Grass GD, Perez BA, Dilling TJ, Strosberg J, Rosenberg SA. PMID: 36708788; PMCID: PMC10845843.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Approaches to the Management of Metastatic Adenoid Cystic Carcinoma. Cancers (Basel). 2022 Nov 20; 14(22). Lee RH, Wai KC, Chan JW, Ha PK, Kang H. PMID: 36428790; PMCID: PMC9688467.
      View in: PubMed   Mentions: 9  
    10. Just Because You Could, Does Not Mean You Should. Int J Radiat Oncol Biol Phys. 2022 Nov 01; 114(3):384. Sinha S, Chan JW. PMID: 36152644.
      View in: PubMed   Mentions:    Fields:    
    11. The Role of Chemotherapy Plus Immune Checkpoint Inhibitors in Oncogenic-Driven NSCLC: A University of California Lung Cancer Consortium Retrospective Study. JTO Clin Res Rep. 2022 Dec; 3(12):100427. Benjamin DJ, Chen S, Eldredge JB, Schokrpur S, Li D, Quan Z, Chan JW, Cummings AL, Daly ME, Goldman JW, Gubens MA, Harris JP, Onaitis MW, Zhu VW, Patel SP, Kelly K. PMID: 36426286; PMCID: PMC9679033.
      View in: PubMed   Mentions: 8  
    12. 18F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results from NRG-HN002. J Nucl Med. 2023 03; 64(3):362-367. Subramaniam RM, DeMora L, Yao M, Yom SS, Gillison M, Caudell JJ, Waldron J, Xia P, Chung CH, Truong MT, Echevarria M, Chan JW, Geiger JL, Mell L, Seaward S, Thorstad WL, Beitler JJ, Sultanem K, Blakaj D, Le QT. PMID: 36215572; PMCID: PMC10071810.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Longitudinal Analysis of Swallowing Displacement Kinematics After Oropharyngeal Cancer Treatment. Laryngoscope. 2023 06; 133(6):1339-1348. Kidane J, Laus J, Gulati A, Gochman GE, Schneider SL, Chan JW, Yom SS, Ha P, Boscardin WJ, Ryan WR, Ma Y. PMID: 36054296.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Feasibility of accelerated image-guided high-dose-rate interstitial brachytherapy with inverse planning simulated annealing (IPSA-HDRBT) for post-operative treatment of pathologically node-negative squamous cell carcinomas of the oral tongue. Brachytherapy. 2022 Sep-Oct; 21(5):686-691. Cheung CK, Chew J, Wai K, Calkins SM, Ha PK, Ryan WR, Cunha A, Yom SS, Hsu IC, Chan JW. PMID: 35715306.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Adverse radiation effect and freedom from progression following repeat stereotactic radiosurgery for brain metastases. J Neurosurg. 2023 01 01; 138(1):104-112. Sneed PK, Chan JW, Ma L, Braunstein SE, Theodosopoulos PV, Fogh SE, Nakamura JL, Boreta L, Raleigh DR, Ziemer BP, Morin O, Hervey-Jumper SL, McDermott MW. PMID: 35594891.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    16. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat Genet. 2022 05; 54(5):649-659. Choudhury A, Magill ST, Eaton CD, Prager BC, Chen WC, Cady MA, Seo K, Lucas CG, Casey-Clyde TJ, Vasudevan HN, Liu SJ, Villanueva-Meyer JE, Lam TC, Pu JK, Li LF, Leung GK, Swaney DL, Zhang MY, Chan JW, Qiu Z, Martin MV, Susko MS, Braunstein SE, Bush NAO, Schulte JD, Butowski N, Sneed PK, Berger MS, Krogan NJ, Perry A, Phillips JJ, Solomon DA, Costello JF, McDermott MW, Rich JN, Raleigh DR. PMID: 35534562; PMCID: PMC9374001.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    17. Safety of accelerated hypofractionated whole pelvis radiation therapy prior to high dose rate brachytherapy or stereotactic body radiation therapy prostate boost. Radiat Oncol. 2022 Jan 20; 17(1):12. Phuong C, Chan JW, Ni L, Wall P, Mohamad O, Wong AC, Hsu IC, Chang AJ. PMID: 35057827; PMCID: PMC8772149.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Artificial Intelligence-Guided Prediction of Dental Doses Before Planning of Radiation Therapy for Oropharyngeal Cancer: Technical Development and Initial Feasibility of Implementation. Adv Radiat Oncol. 2022 Mar-Apr; 7(2):100886. Chan JW, Hohenstein N, Carpenter C, Pattison AJ, Morin O, Valdes G, Sanchez CT, Perkins J, Perkins J, Solberg TD, Yom SS. PMID: 35387423; PMCID: PMC8977910.
      View in: PubMed   Mentions: 3  
    19. Adverse radiation effects in volume-staged radiosurgery for large arteriovenous malformations: a multiinstitutional study. J Neurosurg. 2022 Feb 01; 136(2):503-511. Seymour ZA, Chan JW, McDermott MW, Grills I, Ye H, Kano H, Lehocky CA, Jacobs RC, Lunsford LD, Chytka T, Lišcák R, Lee CC, Yang HC, Ding D, Sheehan JP, Feliciano CE, Rodriguez-Mercado R, Chiang VL, Hess JA, Sommaruga S, McShane B, Lee JYK, Vasas LT, Kaufmann AM, Sneed PK. PMID: 34450589.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma? Adv Radiat Oncol. 2021 Nov-Dec; 6(6):100764. Ahmad TR, Vasudevan HN, Lazar AA, Chan JW, George JR, Alvarado MD, Yu SS, Daud A, Yom SS. PMID: 34485762; PMCID: PMC8408430.
      View in: PubMed   Mentions: 1  
    21. Timing of Urgent Inpatient Palliative Radiation Therapy. Adv Radiat Oncol. 2021 May-Jun; 6(3):100670. Wu SY, Yee E, Chan JW, Chapman CH, Boreta L, Braunstein SE. PMID: 33817413; PMCID: PMC8005735.
      View in: PubMed   Mentions: 1  
    22. Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002). J Clin Oncol. 2021 03 20; 39(9):956-965. Yom SS, Torres-Saavedra P, Caudell JJ, Waldron JN, Gillison ML, Xia P, Truong MT, Kong C, Jordan R, Subramaniam RM, Yao M, Chung CH, Geiger JL, Chan JW, O'Sullivan B, Blakaj DM, Mell LK, Thorstad WL, Jones CU, Banerjee RN, Lominska C, Le QT. PMID: 33507809; PMCID: PMC8078254.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCellsCTClinical Trials
    23. Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study. EJNMMI Res. 2020 Oct 22; 10(1):128. Lawhn-Heath C, Yom SS, Liu C, Villanueva-Meyer JE, Aslam M, Smith R, Narwal M, Juarez R, Behr SC, Pampaloni MH, Chan JW, Glastonbury CM, Hope TA, Flavell RR. PMID: 33090273; PMCID: PMC7581659.
      View in: PubMed   Mentions: 15  
    24. Will the COVID Pandemic Lead to Uncounted Cancer Deaths in the Future? Int J Radiat Oncol Biol Phys. 2020 10 01; 108(2):351-352. Chan JW, Lee VHF. PMID: 32890510; PMCID: PMC7462880.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    25. Estrogen/progesterone receptor and HER2 discordance between primary tumor and brain metastases in breast cancer and its effect on treatment and survival. Neuro Oncol. 2020 09 29; 22(9):1359-1367. Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP. PMID: 32034917; PMCID: PMC7523450.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    26. Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial. JAMA Netw Open. 2020 09 01; 3(9):e209750. Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS. PMID: 32997124; PMCID: PMC7527870.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    27. DoseGAN: a generative adversarial network for synthetic dose prediction using attention-gated discrimination and generation. Sci Rep. 2020 07 06; 10(1):11073. Kearney V, Chan JW, Wang T, Perry A, Descovich M, Morin O, Yom SS, Solberg TD. PMID: 32632116; PMCID: PMC7338467.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    28. Improved Tumor Control Related to Radiotherapy Technological Development for Hypopharyngeal Cancer. Laryngoscope. 2021 02; 131(2):E452-E458. Susko MS, Lazar AA, Dhar S, Chan JW, Shiao SL, Chapman CH, Johnson J, Quivey JM, Ryan WR, Heaton CM, Ha PK, Yom SS. PMID: 32396214.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Salvage Strategies for Neck Recurrences Are Individualized. Int J Radiat Oncol Biol Phys. 2020 04 01; 106(5):903-904. Chan JW. PMID: 32171460.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Attention-Aware Discrimination for MR-to-CT Image Translation Using Cycle-Consistent Generative Adversarial Networks. Radiol Artif Intell. 2020 Mar; 2(2):e190027. Kearney V, Ziemer BP, Perry A, Wang T, Chan JW, Ma L, Morin O, Yom SS, Solberg TD. PMID: 33937817; PMCID: PMC8017410.
      View in: PubMed   Mentions: 17     Fields:    
    31. Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today. Int J Radiat Oncol Biol Phys. 2020 06 01; 107(2):334-343. Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP. PMID: 32084525; PMCID: PMC7276246.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    32. Diagnosis, Staging, Radiation Treatment Response Assessment, and Outcome Prognostication of Head and Neck Cancers Using PET Imaging: A Systematic Review. PET Clin. 2020 Jan; 15(1):65-75. Hohenstein NA, Chan JW, Wu SY, Tahir P, Yom SS. PMID: 31735303.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. Dose response and architecture in volume staged radiosurgery for large arteriovenous malformations: A multi-institutional study. Radiother Oncol. 2020 03; 144:180-188. Seymour ZA, Chan JW, Sneed PK, Kano H, Lehocky CA, Jacobs RC, Ye H, Chytka T, Liscak R, Lee CC, Yang HC, Ding D, Sheehan J, Feliciano CE, Rodriguez-Mercado R, Chiang VL, Hess JA, Sommaruga S, McShane B, Lee J, Vasas LT, Kaufmann AM, Grills I, McDermott MW. PMID: 31835173.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Attention-enabled 3D boosted convolutional neural networks for semantic CT segmentation using deep supervision. Phys Med Biol. 2019 07 02; 64(13):135001. Kearney V, Chan JW, Wang T, Perry A, Yom SS, Solberg TD. PMID: 31181561.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    35. Dedicated Diagnostic Radiology/Radiation Oncology Rounds: Added Value Beyond Traditional Tumor Boards. Curr Probl Diagn Radiol. 2020 Jul - Aug; 49(4):248-253. Kallianos KG, Muhoozi BN, Gottschalk A, Yom SS, Chan JW, Henry TS, Elicker BM, Ordovas KG, Naeger DM. PMID: 31153661.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. A convolutional neural network algorithm for automatic segmentation of head and neck organs at risk using deep lifelong learning. Med Phys. 2019 May; 46(5):2204-2213. Chan JW, Kearney V, Haaf S, Wu S, Bogdanov M, Reddick M, Dixit N, Sudhyadhom A, Chen J, Yom SS, Solberg TD. PMID: 30887523.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    37. Advances in multidisciplinary therapy for meningiomas. Neuro Oncol. 2019 01 14; 21(Suppl 1):i18-i31. Brastianos PK, Galanis E, Butowski N, Chan JW, Dunn IF, Goldbrunner R, Herold-Mende C, Ippen FM, Mawrin C, McDermott MW, Sloan A, Snyder J, Tabatabai G, Tatagiba M, Tonn JC, Wen PY, Aldape K, Nassiri F, Zadeh G, Jenkinson MD, Raleigh DR, International Consortium on Meningiomas. PMID: 30649489; PMCID: PMC6347080.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    38. Ultraviolet light-related DNA damage mutation signature distinguishes cutaneous from mucosal or other origin for head and neck squamous cell carcinoma of unknown primary site. Head Neck. 2019 06; 41(6):E82-E85. Chan JW, Yeh I, El-Sayed IH, Algazi AP, Glastonbury CM, Ha PK, Yom SS, van Zante A. PMID: 30633411.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    39. DoseNet: a volumetric dose prediction algorithm using 3D fully-convolutional neural networks. Phys Med Biol. 2018 12 04; 63(23):235022. Kearney V, Chan JW, Haaf S, Descovich M, Solberg TD. PMID: 30511663.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    40. The application of artificial intelligence in the IMRT planning process for head and neck cancer. Oral Oncol. 2018 12; 87:111-116. Kearney V, Chan JW, Valdes G, Solberg TD, Yom SS. PMID: 30527225.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansPHPublic Health
    41. Reducing radiation-related morbidity in the treatment of nasopharyngeal carcinoma. Future Oncol. 2017 Feb; 13(5):425-431. Chan JW, Parvathaneni U, Yom SS. PMID: 27875901.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    42. Words of Wisdom. Re: Genomic Classifier Identifies Men with Adverse Pathology After Radical Prostatectomy Who Benefit from Adjuvant Radiation Therapy. Eur Urol. 2016 Mar; 69(3):539-40. Chan J, Roach M. PMID: 26867726.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. A Predictive Genetic Signature for Response to Fluoropyrimidine-Based Neoadjuvant Chemoradiation in Clinical Stage II and III Rectal Cancer. Front Oncol. 2013; 3:288. Chan J, Kinsella MT, Willis JE, Hu H, Reynolds H, Delaney C, McCulla A, Deharo S, Ahdesmäki M, Allen WL, Johnston PG, Kinsella TJ. PMID: 24324931; PMCID: PMC3839295.
      View in: PubMed   Mentions: 5  
    44. UVA phototransduction drives early melanin synthesis in human melanocytes. Curr Biol. 2011 Nov 22; 21(22):1906-11. Wicks NL, Chan JW, Najera JA, Ciriello JM, Oancea E. PMID: 22055294; PMCID: PMC3586554.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    45. Fabrication of nanopores with embedded annular electrodes and transverse carbon nanotube electrodes. J Phys Condens Matter. 2010 Nov 17; 22(45):454114. Jiang Z, Mihovilovic M, Chan J, Stein D. PMID: 21339601.
      View in: PubMed   Mentions: 13     Fields:    
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