Skip to main content
. 2011 Oct 10;121(11):4409–4419. doi: 10.1172/JCI58097

Figure 3. Fgf10 mediates epithelial repair independent of Wnt ligands in part by activating/enhancing β-catenin signaling in the epithelium.

Figure 3

β-gal staining (A–J) and β-gal staining with coimmunostaining for Scgb1a1 (K–O) or CGRP (P–T) on lungs 7 days after naphthalene treatment from TOPGAL (A, F, K, and P), dox-induced Rosa26-rtTA;Tet-Fgf10;TOPGAL (B, G, L, and Q), dox-induced Rosa26-rtTa;Tet-sFgfr2b;TOPGAL (C, H, M, and R), dox-induced Rosa26-rtTa;Tet-Dkk1;TOPGAL (D, I, N, and S), and dox-induced Rosa26-rtTa;Tet-Dkk1;Tet-Fgf10;TOPGAL mice (E, J, O, and T). Scale bars: 2,000 μm (A–E); 500 μm (F–J); 50 μm (K–T).