(Q85123423)

English

Hypoxia-Induced Mitogenic Factor (HIMF/FIZZ1/RELMα) Increases Lung Inflammation and Activates Pulmonary Microvascular Endothelial Cells via an IL-4–Dependent Mechanism

scientific article published on November 1, 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889544%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889544%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Hypoxia-Induced Mitogenic Factor (HIMF/FIZZ1/RELMα) Increases Lung Inflammation and Activates Pulmonary Microvascular Endothelial Cells via an IL-4–Dependent Mechanism (English)

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10.4049/JIMMUNOL.0904021

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25 July 2024

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Kazuyo Yamaji-Kegan

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14 February 2020

Qingning Su

2

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14 February 2020

Chris Cheadle

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14 February 2020

Daniel J. Angelini

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25 July 2024

Allen C. Myers

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Roger A. Johns

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1 October 2010

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14 February 2020

1 November 2010

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25 July 2024

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25 July 2024

Journal of Immunology

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14 February 2020

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14 February 2020

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14 February 2020

5539-5548

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14 February 2020

Primary pulmonary hypertension

1

1 reference

10.4049/JIMMUNOL.0904021

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25 July 2024

FIZZ1/RELMα, a Novel Hypoxia-Induced Mitogenic Factor in Lung With Vasoconstrictive and Angiogenic Properties

2

1 reference

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25 July 2024

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

3

1 reference

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Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6.

4

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Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.

5

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Bruton's tyrosine kinase (BTK) is a binding partner for hypoxia induced mitogenic factor (HIMF/FIZZ1) and mediates myeloid cell chemotaxis

6

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Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension

7

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Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM alpha) recruits bone marrow-derived cells to the murine pulmonary vasculature

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FIZZ1 stimulation of myofibroblast differentiation

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The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism

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Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.

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10.4049/JIMMUNOL.0904021

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889544%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889544%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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