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Is passive immunization for Alzheimer's disease 'alive and well' or 'dead and buried'?
scientific article published on 01 April 2009
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Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Is passive immunization for Alzheimer's disease 'alive and well' or 'dead and buried'?
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
passive immunization
1 reference
based on heuristic
inferred from title
Alzheimer's disease
1 reference
based on heuristic
inferred from title
author
Gregory A Jicha
series ordinal
1
object named as
Gregory A Jicha
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
publication date
1 April 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Expert Opinion on Biological Therapy
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
481-491
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
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Disease-modifying therapies in Alzheimer's disease
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Amyloid-beta antibody treatment leads to rapid normalization of plaque-induced neuritic alterations.
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Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease
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12 December 2020
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Mild cognitive impairment: to treat or not to treat
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Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage
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12 December 2020
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Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis
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12 December 2020
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Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease
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12 December 2020
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Vaccine development for Alzheimer's disease
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12 December 2020
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The mechanisms of neurodegenerative processes and current pharmacotherapy of Alzheimer's disease
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12 December 2020
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Alzheimer's disease: the benefits of early treatment
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12 December 2020
based on heuristic
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Passive immunization of the Abeta42(43) C-terminal-specific antibody BC05 in a mouse model of Alzheimer's disease
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12 December 2020
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Biomarkers for Alzheimer's disease--clinical needs and application.
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12 December 2020
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Cerebral hemorrhage after passive anti-Abeta immunotherapy
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12 December 2020
based on heuristic
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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
1 reference
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PubMed
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12 December 2020
based on heuristic
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Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model
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12 December 2020
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Posterior reversible encephalopathy syndrome associated with IVIG in a patient with Guillain-Barré syndrome
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12 December 2020
based on heuristic
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Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.
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12 December 2020
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Intravenous immunoglobulin and the kidney--a two-edged sword
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12 December 2020
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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
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12 December 2020
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Developing injectable immunoglobulins to treat cognitive impairment in Alzheimer's disease
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Absence of beta-amyloid deposits after immunization in Alzheimer disease with Lewy body dementia
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12 December 2020
based on heuristic
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In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence supporting a role for anti-Abeta antibodies in the treatment of Alzheimer's disease
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12 December 2020
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Immunotherapy reduces vascular amyloid-beta in PDAPP mice.
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12 December 2020
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inferred from PubMed ID database lookup
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
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12 December 2020
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Intravenous immunoglobulins in neurological disorders: safety issues
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12 December 2020
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Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention.
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Toward modeling hemorrhagic and encephalitic complications of Alzheimer amyloid-beta vaccination in nonhuman primates
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Intravenous immunoglobulin induced-nephropathy: a complication of IVIG therapy
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12 December 2020
based on heuristic
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Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels
1 reference
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12 December 2020
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Posterior reversible encephalopathy and Guillain-Barré syndrome in a single patient: coincidence or causative relation?
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Posterior reversible encephalopathy induced by intravenous immunoglobulin
1 reference
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12 December 2020
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18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease.
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunization in Alzheimer's disease: naïve hope or realistic clinical potential?
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Posterior reversible encephalopathy complicating intravenous immunoglobulins in a patient with miller-fisher syndrome.
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PubMed
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis
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Acute renal failure after large doses of intravenous immune globulin
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Antibody-based approaches in Alzheimer's research: safety, pharmacokinetics, metabolism, and analytical tools
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Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease
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Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease
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Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration
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Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.
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Thromboembolic events as an emerging adverse effect during high-dose intravenous immunoglobulin therapy in elderly patients: a case report and discussion of the relevant literature
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Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease
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Active and passive immunotherapy for neurodegenerative disorders
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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
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Drug-induced aseptic meningitis: diagnosis and management
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12 December 2020
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Molecular basis for passive immunotherapy of Alzheimer's disease
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Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial
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Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
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12 December 2020
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Abeta42 immunization in Alzheimer's disease generates Abeta N-terminal antibodies
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12 December 2020
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Early diagnosis and treatment of Alzheimer's disease
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Pharmaceutical treatment for cognitive deficits in Alzheimer's disease and other neurodegenerative conditions: exploring new territory using traditional tools and established maps
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Beta-amyloidbased immunotherapy as a treatment of Alzheimers disease
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Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models
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12 December 2020
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Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging.
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12 December 2020
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Intravenous gammglobulin-associated acute renal failure
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12 December 2020
based on heuristic
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Disease-modifying therapies for Alzheimer disease: challenges to early intervention
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12 December 2020
based on heuristic
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Intravenous immunoglobulin and Alzheimer's disease immunotherapy.
1 reference
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
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Antibody against C-terminal Abeta selectively elevates plasma Abeta
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Alzhemed: a potential treatment for Alzheimer's disease
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12 December 2020
based on heuristic
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Limited clearance of pre-existing amyloid plaques after intracerebral injection of Abeta antibodies in two mouse models of Alzheimer disease
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12 December 2020
based on heuristic
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Which is a better target for AD immunotherapy, A beta or tau?
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12 December 2020
based on heuristic
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Alzheimer disease: mechanistic understanding predicts novel therapies
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12 December 2020
based on heuristic
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Amyloid-beta immunisation for Alzheimer's disease
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
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Thrombosis complicating high dose intravenous immunoglobulin: report of three cases and review of the literature
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12 December 2020
based on heuristic
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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
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12 December 2020
based on heuristic
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Assembly of Alzheimer's amyloid-beta fibrils and approaches for therapeutic intervention.
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prevention and reduction of AD-type pathology in PDAPP mice immunized with A beta 1-42.
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Developing novel immunogens for an effective, safe Alzheimer's disease vaccine
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mild cognitive impairment: emerging therapeutics
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Has the amyloid cascade hypothesis for Alzheimer's disease been proved?
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mechanisms of A beta plaque clearance following passive A beta immunization
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https://pubmed.ncbi.nlm.nih.gov/19344284
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clinical immunologic approaches for the treatment of Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Allergen immunotherapy for allergic rhinitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peripheral and central biodistribution of (111)In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunotherapy of Alzheimer's disease (AD): from murine models to anti-amyloid beta (Abeta) human monoclonal antibodies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunotherapy as treatment for Alzheimer’s disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Good and Bad Amyloid Antibodies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amyloid-beta vaccination, but not nitro-nonsteroidal anti-inflammatory drug treatment, increases vascular amyloid and microhemorrhage while both reduce parenchymal amyloid
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel Abeta immunogens: is shorter better?
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neurological complications of intravenous immunoglobulin (IVIg) therapy: an illustrative case of acute encephalopathy following IVIg therapy and a review of the literature.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The many faces of amyloid beta in Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19344284
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1517/14712590902828285
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PMC publication ID
2704502
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
19344284
1 reference
stated in
Europe PubMed Central
PMC publication ID
2704502
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19344284%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
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