(Q81232006)

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Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

scientific article published on 18 September 2005

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7 January 2020

Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells (English)

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7 January 2020

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7 January 2020

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Orit Kollet

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7 January 2020

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Tsvee Lapidot

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7 January 2020

Alexander Kalinkovich

4

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Alexander Kalinkovich

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7 January 2020

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Ayelet Dar

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7 January 2020

Polina Goichberg

2

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Polina Goichberg

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7 January 2020

10

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Izhar Hardan

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7 January 2020

9

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Arnon Nagler

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7 January 2020

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Vera Shinder

3

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7 January 2020

Neta Netzer

6

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7 January 2020

Raanan Margalit

7

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7 January 2020

Marion Zsak

8

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7 January 2020

Igor Resnick

11

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7 January 2020

publication date

18 September 2005

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7 January 2020

Nature Immunology

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7 January 2020

6

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7 January 2020

10

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7 January 2020

1038-1046

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7 January 2020

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

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The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

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7 January 2021

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

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Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

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7 January 2021

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Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

1 reference

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7 January 2021

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Selective secretion of chemoattractants for haemopoietic progenitor cells by bone marrow endothelial cells: a possible role in homing of haemopoietic progenitor cells to bone marrow

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The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow

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Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

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7 January 2021

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Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells.

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7 January 2021

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Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells.

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7 January 2021

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

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HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver

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Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.

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G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

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Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

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Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells

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CXCR-4 desensitization is associated with tissue localization of hemopoietic progenitor cells

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Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells

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Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells

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7 January 2021

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7 January 2021

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Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.

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7 January 2021

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7 January 2021

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Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

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Proteoglycans on bone marrow endothelial cells bind and present SDF-1 towards hematopoietic progenitor cells

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Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice

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HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

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A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia.

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Europe PubMed Central

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7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

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7 January 2020

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