(Q79291242)

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21 December 2019

title

IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha (English)

1 reference

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21 December 2019

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα (English)

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1 April 2024

1 reference

1 reference

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1 April 2024

6

Michael Karin

1 reference

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21 December 2019

author name string

Shin Maeda

1

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21 December 2019

Lufen Chang

2

1 reference

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21 December 2019

Zhi-Wei Li

3

1 reference

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21 December 2019

Jun-Li Luo

4

1 reference

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21 December 2019

Hyam Leffert

5

1 reference

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21 December 2019

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14614859

1 April 2024

publication date

1 November 2003

1 reference

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full work available at URL

21 December 2019

http://www.cell.com/article/S1074761303003017/pdf

file format

Portable Document Format

online access status

open access

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1 April 2024

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1 April 2024

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1 April 2024

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21 December 2019

volume

19

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21 December 2019

issue

5

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21 December 2019

page(s)

725-737

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

21 December 2019

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7 January 2021

Increased plasma tumor necrosis factor in severe alcoholic hepatitis

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7 January 2021

Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy

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7 January 2021

A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

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7 January 2021

JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

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7 January 2021

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

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7 January 2021

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

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7 January 2021

Galactosamine hepatitis: key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death

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7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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7 January 2021

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

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7 January 2021

Missing pieces in the NF-kappaB puzzle

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7 January 2021

Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitis

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7 January 2021

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

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7 January 2021

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

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7 January 2021

NF-kappa B: arresting a major culprit in cancer

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7 January 2021

NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis

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7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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7 January 2021

NFkappaB prevents apoptosis and liver dysfunction during liver regeneration

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7 January 2021

NF-kappaB at the crossroads of life and death

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7 January 2021

Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A

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7 January 2021

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

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7 January 2021

JunD mediates survival signaling by the JNK signal transduction pathway

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7 January 2021

High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

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7 January 2021

IKKβ Is Required for Peripheral B Cell Survival and Proliferation

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7 January 2021

Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

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7 January 2021

Enhanced tumour necrosis factor and interleukin-1 in fulminant hepatic failure

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7 January 2021

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

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7 January 2021

LPS-induced liver injury in D-galactosamine-sensitized mice requires secreted TNF-alpha and the TNF-p55 receptor

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Hepatocellular carcinoma

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7 January 2021

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

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DNA excision in liver by an albumin-Cre transgene occurs progressively with age

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7 January 2021

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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7 January 2021

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

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7 January 2021

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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Limb and skin abnormalities in mice lacking IKKalpha

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7 January 2021

Critical contribution of liver natural killer T cells to a murine model of hepatitis

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7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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7 January 2021

Inhibition of JNK activation through NF-kappaB target genes

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7 January 2021

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A T cell-dependent experimental liver injury in mice inducible by concanavalin A

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7 January 2021

Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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7 January 2021

NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis.

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7 January 2021

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

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7 January 2021

Mechanisms of hepatic toxicity. I. TNF-induced liver injury

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1 April 2024

Identifiers

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21 December 2019

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