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English
Molecular aspects of multiple myeloma
scientific article published on 01 October 2002
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1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Molecular aspects of multiple myeloma
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
main subject
multiple myeloma
1 reference
based on heuristic
inferred from title
author name string
G Pratt
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
publication date
1 October 2002
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
published in
Journal of Clinical Pathology
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
volume
55
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
page(s)
273-283
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
cites work
Expression of the bcl-2 gene in human multiple myeloma cell lines and normal plasma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Karyotype in multiple myeloma and plasma cell leukaemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32).
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypodiploidy is a major prognostic factor in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cytogenetic analysis of 280 patients with multiple myeloma and related disorders: primary breakpoints and clinical correlations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p16(INK4a) and p15(INK4b) gene methylations in plasma cells from monoclonal gammopathy of undetermined significance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple myeloma and the translocation t(11;14)(q13;q32): a report on 13 cases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
v-maf, a viral oncogene that encodes a "leucine zipper" motif
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The retinoblastoma gene (RB-1) status in multiple myeloma: a report on 35 cases.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The interleukin-6 receptor alpha-chain (CD126) is expressed by neoplastic but not normal plasma cells.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasias
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Loss of PTEN expression leading to high Akt activation in human multiple myelomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Monoclonal gammopathy of undetermined significance: chromosome changes are a common finding within bone marrow plasma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bcl-2 protein expression is not related to short survival in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin 6-mediated up-regulation of bcl-xL
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Frequent hypermethylation of p16 and p15 genes in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of new nonrandom translocations in multiple myeloma with multicolor spectral karyotyping
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interphase fluorescence in situ hybridization (FISH) as a powerful tool for the detection of aneuploidy in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cellular DNA content as a marker of human multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutations of the p53 gene in human myeloma cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interleukin-6 promotes multiple myeloma cell growth via phosphorylation of retinoblastoma protein.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Analysis of the p16INK4A, p15INK4B and p18INK4C genes in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prognostic implications of tumor cell DNA and RNA content in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hyaluronic acid induces survival and proliferation of human myeloma cells through an interleukin-6-mediated pathway involving the phosphorylation of retinoblastoma protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cytogenetic study in multiple myeloma at diagnosis: comparison of two techniques
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Illegitimate switch recombinations are present in approximately half of primary myeloma tumors, but do not relate to known prognostic indicators or survival
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosome translocations in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insertional events as well as translocations may arise during aberrant immunoglobulin switch recombination in a patient with multiple myeloma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The role of p53, bcl-2 and bax network in dexamethasone induced apoptosis in multiple myeloma cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Plasma cell karyotype in multiple myeloma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular cytogenetic abnormalities in multiple myeloma and plasma cell leukemia measured using comparative genomic hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A variant chromosome translocation at 11q13 identifying PRAD1/cyclin D1 as the BCL-1 gene
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The myeloma-associated oncogene fibroblast growth factor receptor 3 is transforming in hematopoietic cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
bcl-2 expression in plasma cells from neoplastic gammopathies and reactive plasmacytosis: a comparative study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mechanisms of chromosomal translocations in B cell lymphomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Use of fluorescence in situ hybridization for retrospective detection of aneuploidy in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Monosomy 13 is associated with the transition of monoclonal gammopathy of undetermined significance to multiple myeloma. Intergroupe Francophone du Myélome.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High incidence of deletions but infrequent inactivation of the retinoblastoma gene in human myeloma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Introduction of an activated N-ras oncogene alters the growth characteristics of the interleukin 6-dependent myeloma cell line ANBL6.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Gene rearrangement and overexpression of PRAD1 in lymphoid malignancy with t(11;14)(q13;q32) translocation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kaposi's sarcoma-associated herpesvirus and multiple myeloma: lack of criteria for causality
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Fas-L up-regulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prognostic value of cytogenetics in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
WWOX, the FRA16D gene, behaves as a suppressor of tumor growth
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple myeloma: almost all patients are cytogenetically abnormal
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by double-color fluorescent in situ hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p53 and RAS gene mutations in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Analysis of FGFR3 gene mutations in multiple myeloma patients with t(4;14)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interleukin-6 in human multiple myeloma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insertion of excised IgH switch sequences causes overexpression of cyclin D1 in a myeloma tumor cell
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple myeloma: increasing evidence for a multistep transformation process
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interleukin-6 overcomes p21WAF1 upregulation and G1 growth arrest induced by dexamethasone and interferon-gamma in multiple myeloma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cytogenetic findings in 200 patients with multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multicolor spectral karyotyping identifies new recurring breakpoints and translocations in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expanded range of 11q13 breakpoints with differing patterns of cyclin D1 expression in B-cell malignancies.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel therapeutic targets in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Improved cytogenetic analysis of bone marrow plasma cells after cytokine stimulation in multiple myeloma: a report on 46 patients.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
New insights into role of microenvironment in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of CDK4 and p16INK4A in interleukin-6-mediated growth of multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosome 13 abnormalities identified by FISH analysis and serum beta2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of N-Ras codon 61 mutations in subpopulations of tumor cells in multiple myeloma at presentation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosome 11 translocation breakpoints at the PRAD1/cyclin D1 gene locus in centrocytic lymphoma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular analysis of 11q13 breakpoints in multiple myeloma.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cytogenetics in multiple myeloma: a multicenter study of 24 patients with t(11;14)(q13;q32) or its variant
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular breakpoints of t(11;14)(q13;q32) in multiple myeloma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12354927
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1136/MP.55.5.273
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
PMC publication ID
1187254
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
PubMed publication ID
12354927
1 reference
stated in
Europe PubMed Central
PMC publication ID
1187254
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12354927%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 December 2019
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