(Q73653416)

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Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy

scientific article published on 10 July 2003

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5 November 2019

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy (English)

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5 November 2019

David C. Parker

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5 November 2019

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Tara J Dillon

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5 November 2019

Vladamir Karpitski

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5 November 2019

Scott A Wetzel

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5 November 2019

Andréy S Shaw

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5 November 2019

Philip J S Stork

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5 November 2019

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10 July 2003

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

278

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5 November 2019

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5 November 2019

35940-35949

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5 November 2019

The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells

1 reference

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21 January 2018

A ras-related gene with transformation suppressor activity

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CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

1 reference

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21 January 2018

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

1 reference

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21 January 2018

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

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21 January 2018

Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes

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21 January 2018

Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection

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21 January 2018

Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes

1 reference

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21 January 2018

Combinatorial effect of T-cell receptor ligation and CD45 isoform expression on the signaling contribution of the small GTPases Ras and Rap1.

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21 January 2018

Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses

1 reference

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21 January 2018

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

1 reference

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21 January 2018

The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion

1 reference

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21 January 2018

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

1 reference

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21 January 2018

Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein

1 reference

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21 January 2018

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

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21 January 2018

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

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21 January 2018

The requirement of specific membrane domains for Raf-1 phosphorylation and activation

1 reference

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21 January 2018

Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.

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21 January 2018

Differential effects of cAMP in neurons and astrocytes. Role of B-raf

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21 January 2018

Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy

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21 January 2018

Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by

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21 January 2018

The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor.

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21 January 2018

Live-cell dynamics and the role of costimulation in immunological synapse formation

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21 January 2018

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

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21 January 2018

Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies

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21 January 2018

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

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21 January 2018

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

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21 January 2018

Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene

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Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

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21 January 2018

Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naive CD4+ T cells

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21 January 2018

Transactivation by AP-1 is a molecular target of T cell clonal anergy

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21 January 2018

JNK is involved in signal integration during costimulation of T lymphocytes.

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Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

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Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways

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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

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Involvement of p21ras activation in T cell CD69 expression

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Control of T lymphocyte signal transduction through clonal anergy

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Negative transcriptional regulation in anergic T cells

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A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

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10.1074/JBC.M301506200

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12855697%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12855697%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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