(Q7276721)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62745

small GTPase Rho

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62745

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

GDP binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

GTP binding

Post-translational modifications of p21rho proteins

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

31 October 2017

protein binding

3 references

8 April 2019

RHO binding to FAM65A regulates Golgi reorientation during cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

GTPase activity

A novel ras-related gene family

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

GTP binding

Post-translational modifications of p21rho proteins

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

protein kinase binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

cell component

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

late endosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

late endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

focal adhesion

1 reference

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

5 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

31 October 2017

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

31 October 2017

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

31 October 2017

Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

early endosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

3 references

8 April 2019

8 April 2019

Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

extracellular exosome

1 reference

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

intracellular anatomical structure

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

1 reference

31 October 2017

cytoplasm

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

focal adhesion

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

cell cortex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

cell division site

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

intracellular membrane-bounded organelle

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

extracellular exosome

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

biological process

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

regulation of cell migration

IGI

1 reference

31 October 2017

Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

endosome to lysosome transport

IGI

1 reference

8 April 2019

Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

endothelial tube morphogenesis

1 reference

8 April 2019

MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

positive regulation of endothelial cell migration

1 reference

8 April 2019

MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

platelet activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

1 reference

31 October 2017

cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

negative regulation of cell migration

1 reference

8 April 2019

Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

Rho protein signal transduction

1 reference

31 October 2017

A novel ras-related gene family

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

cellular response to ionizing radiation

1 reference

8 April 2019

The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

intracellular protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

regulation of small GTPase mediated signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

cellular response to hydrogen peroxide

1 reference

8 April 2019

The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

small GTPase mediated signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

positive regulation of apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

3 references

8 April 2019

ISS

8 April 2019

The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62745&geneProductId=UniProtKB:P62745

1 reference

31 October 2017

mitotic cytokinesis

1 reference

8 April 2019

Dissecting the role of Rho-mediated signaling in contractile ring formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

1 reference

8 April 2019

actin filament organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

regulation of cell shape

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

cell migration

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

regulation of cell migration

establishment or maintenance of actin cytoskeleton polarity

IGI

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

regulation of actin cytoskeleton organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

actin filament bundle assembly

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62745

small GTP-binding protein domain

Gene Atlas image

PBB GE RHOB 212099 at fs.png
732 × 530; 11 KB

0 references

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62745

Identifiers

MeSH descriptor ID

D020743

subject named as

rhoB GTP-Binding Protein

0 references

MeSH tree code

D08.811.277.040.330.300.400.700.300

0 references

D12.776.157.325.515.700.300

0 references

D12.776.476.338.400.700.300

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

4 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023