Wikidata

(Q6725886)

English

Mitotic arrest deficient 1 like 1

mammalian protein found in Homo sapiens

  • mitotic checkpoint MAD1 protein homolog
  • mitotic arrest deficient 1-like protein 1
  • MAD1L1
  • tumor protein p53 inducible protein 9
  • hMAD1
  • tax-binding protein 181
  • HsMAD1
  • mitotic-arrest deficient 1, yeast, homolog-like 1
  • MAD1-like protein 1
  • MAD1 mitotic arrest deficient like 1
  • mitotic spindle assembly checkpoint protein MAD1
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No label defined

No description defined

Statements

molecular function
protein binding
determination method
IPI
21 references
retrieved
8 April 2019
stated in
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
A protein domain-based interactome network for C. elegans early embryogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IPI
cell component
kinetochore
determination method
IDA
IEA
6 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IEA
retrieved
5 June 2018
stated in
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
5 June 2018
stated in
Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
5 June 2018
stated in
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
5 June 2018
stated in
RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y6D9&geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
kinetochore
determination method
IBA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IEA
retrieved
8 April 2019
stated in
Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
8 April 2019
stated in
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
8 April 2019
stated in
RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint
GOA
curator
UniProt
UniProt protein ID
Q9Y6D9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6D9
determination method
IBA
biological process
Gene Atlas image
PBB GE MAD1L1 204857 at fs.png
732 × 530; 11 KB
0 references

Identifiers

 
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