(Q54049708)

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Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. (English)

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

multiple drug resistance

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Srour EF

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

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Abonour R

1

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Williams DA

2

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Einhorn L

3

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Hall KM

4

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Chen J

5

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Coffman J

6

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Traycoff CM

7

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Bank A

8

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Kato I

9

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Ward M

10

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Williams SD

11

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Hromas R

12

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Robertson MJ

13

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PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Smith FO

14

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Woo D

15

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

Mills B

16

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24 May 2018

http://europepmc.org/abstract/MED/10835681

Cornetta K

18

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24 May 2018

http://europepmc.org/abstract/MED/10835681

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1 June 2000

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24 May 2018

http://europepmc.org/abstract/MED/10835681

Nature Medicine

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24 May 2018

http://europepmc.org/abstract/MED/10835681

6

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24 May 2018

http://europepmc.org/abstract/MED/10835681

6

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24 May 2018

http://europepmc.org/abstract/MED/10835681

652-658

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24 May 2018

http://europepmc.org/abstract/MED/10835681

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.

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Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation.

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Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy

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Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

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Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor

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The 30/35 kDa chymotryptic fragment of fibronectin enhances retroviral-mediated gene transfer in purified chronic myelogenous leukemia bone marrow progenitors

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Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors

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Improved methods of retroviral vector transduction and production for gene therapy

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Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

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Maintenance chemotherapy with daily oral etoposide following salvage therapy in patients with germ cell tumors

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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

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Differential expression of p53, c-kit, and CD34 in prepubertal and postpubertal testicular germ cell tumors

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21 January 2018

A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs

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21 January 2018

Safety aspects of gene therapy

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21 January 2018

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

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Infection of human cells with murine amphotropic replication-competent retroviruses

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Applications of the polymerase chain reaction in retroviral-mediated gene transfer and the analysis of gene-marked human TIL cells

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Retroviral mediated transfer of the cDNA for human glucocerebrosidase into hematopoietic stem cells of patients with Gaucher disease. A phase I study

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Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients

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Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells.

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Lack of functional Pit-1 and Pit-2 expression on hematopoietic stem cell lines

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Optimization of fibronectin-assisted retroviral gene transfer into human CD34+ hematopoietic cells

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Optimization of retroviral-mediated gene transfer to human NOD/SCID mouse repopulating cord blood cells through a systematic analysis of protocol variables.

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7 January 2021

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Engraftment of gene-marked hematopoietic progenitors in myeloma patients after transplant of autologous long-term marrow cultures

1 reference

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7 January 2021

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Identifiers

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10835681

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