(Q53513869)

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28 December 2019

review article

1 reference

title

The interplay between MYC and HIF in cancer (English)

1 reference

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28 December 2019

1

1 reference

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28 December 2019

Jung-whan Kim

series ordinal

2

1 reference

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28 December 2019

author name string

Ping Gao

series ordinal

3

1 reference

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28 December 2019

Jason Yustein

series ordinal

4

1 reference

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28 December 2019

language of work or name

English

0 references

publication date

1 January 2008

1 reference

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28 December 2019

published in

Nature Reviews Cancer

1 reference

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28 December 2019

volume

8

1 reference

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28 December 2019

issue

1

1 reference

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28 December 2019

page(s)

51-56

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Tumor angiogenesis: cause or consequence of cancer?

28 December 2019

cites work

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Transcriptional regulation and transformation by Myc proteins

31 March 2020

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Hypoxia-inducible factors: central regulators of the tumor phenotype

31 March 2020

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HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

31 March 2020

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Targeting HIF-1 for cancer therapy

31 March 2020

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Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

31 March 2020

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The c-Myc target gene network

31 March 2020

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The Myc/Max/Mad network and the transcriptional control of cell behavior

31 March 2020

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The Max network gone mad.

31 March 2020

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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

31 March 2020

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Global mapping of c-Myc binding sites and target gene networks in human B cells

31 March 2020

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Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

31 March 2020

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Myc and Max homologs in Drosophila

31 March 2020

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Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis

31 March 2020

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Genomic targets of the human c-Myc protein

31 March 2020

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Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development

31 March 2020

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c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

31 March 2020

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Direct activation of RNA polymerase III transcription by c-Myc

31 March 2020

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Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

31 March 2020

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c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

31 March 2020

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Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

31 March 2020

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Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

31 March 2020

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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

31 March 2020

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Hypoxia signalling controls metabolic demand

31 March 2020

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Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

31 March 2020

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

31 March 2020

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ROS: really involved in oxygen sensing

31 March 2020

1 reference

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Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.

31 March 2020

1 reference

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

31 March 2020

1 reference

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

31 March 2020

1 reference

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

31 March 2020

1 reference

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HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

31 March 2020

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Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

31 March 2020

1 reference

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p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest

31 March 2020

1 reference

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Hypoxia inhibits G1/S transition through regulation of p27 expression

31 March 2020

1 reference

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

31 March 2020

1 reference

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HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

31 March 2020

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The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression

31 March 2020

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

31 March 2020

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Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

31 March 2020

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Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a

31 March 2020

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Mxi1 is induced by hypoxia in a HIF-1-dependent manner and protects cells from c-Myc-induced apoptosis.

31 March 2020

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Gene-target recognition among members of the myc superfamily and implications for oncogenesis

31 March 2020

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

31 March 2020

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

31 March 2020

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

31 March 2020

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The myc oncogene: MarvelouslY Complex

31 March 2020

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MYC levels govern hematopoietic tumor type and latency in transgenic mice

31 March 2020

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Conditional transgenic models define how MYC initiates and maintains tumorigenesis

31 March 2020

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p53 mediates apoptosis induced by c-Myc activation in hypoxic or gamma irradiated fibroblasts

31 March 2020

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Antagonism of Myc functions by Arf

31 March 2020

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HIF-dependent antitumorigenic effect of antioxidants in vivo

31 March 2020

1 reference

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The hypoxic response of tumors is dependent on their microenvironment.

31 March 2020

1 reference

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On the Origin of Cancer Cells

31 March 2020

1 reference

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Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

31 March 2020

1 reference

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Akt-dependent transformation: there is more to growth than just surviving

31 March 2020

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Cancer's molecular sweet tooth and the Warburg effect.

31 March 2020

1 reference

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Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting

31 March 2020

1 reference

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Fractal characteristics of tumor vascular architecture during tumor growth and regression

31 March 2020

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Why do cancers have high aerobic glycolysis?

31 March 2020

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Direct comparison of FDG PET and CT findings in patients with lymphoma: initial experience

31 March 2020

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Multifaceted roles of glycolytic enzymes.

31 March 2020

1 reference

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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

31 March 2020

1 reference

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Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

31 March 2020

1 reference

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Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis

31 March 2020

1 reference

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Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

31 March 2020

1 reference

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Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway

31 March 2020

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A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC2274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18046334%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference