(Q53335187)

13 May 2018

http://europepmc.org/abstract/MED/10229234

title

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. (English)

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

1 reference

Chui DH

1

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Tanahashi H

2

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Ozawa K

3

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Ikeda S

4

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Checler F

5

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Ueda O

6

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Suzuki H

7

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Araki W

8

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Inoue H

9

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Shirotani K

10

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Takahashi K

11

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Gallyas F

12

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Tabira T

13

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

language of work or name

English

0 references

publication date

1 May 1999

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

published in

Nature Medicine

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

volume

5

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

issue

5

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

page(s)

560-564

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13 May 2018

http://europepmc.org/abstract/MED/10229234

cites work

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

Presenilin mutations in Alzheimer's disease

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7 January 2021

Familial Alzheimer's disease genes in Japanese.

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7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology

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7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

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7 January 2021

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

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7 January 2021

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

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7 January 2021

Four modified silver methods for thick sections of formaldehyde-fixed mammalian central nervous tissue: 'dark' neurons, perikarya of all neurons, microglial cells and capillaries

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7 January 2021

Formation of "dark" (argyrophilic) neurons of various origin proceeds with a common mechanism of biophysical nature (a novel hypothesis).

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7 January 2021

Amyloid, the presenilins and Alzheimer's disease

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7 January 2021

Alzheimer's disease: a re-examination of the amyloid hypothesis

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7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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7 January 2021

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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7 January 2021

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

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7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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7 January 2021

Neuron loss in APP transgenic mice

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7 January 2021

Proteolytic processing of Alzheimer's disease associated proteins.

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7 January 2021

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

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7 January 2021

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

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7 January 2021

A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.

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7 January 2021

Stress induces neuronal death in the hippocampus of castrated rats

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7 January 2021

Neuronal and glial apoptosis after traumatic spinal cord injury.

1 reference

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7 January 2021

Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiop

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7 January 2021

Immunohistochemical study of Alzheimer's disease using antibodies to synthetic amyloid and fibronectin

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7 January 2021

Identifiers

DOI

10.1038/8438

1 reference

13 May 2018

http://europepmc.org/abstract/MED/10229234

Fatcat ID

release_4k76yfrhtrgatmeysumiivjp24

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4k76yfrhtrgatmeysumiivjp24

24 November 2022

mapped directly with Wikidata item

1 reference

13 May 2018