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English
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.
scientific article published in January 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author
Thomas von Zglinicki
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
R Pilger
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
N Sitte
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 January 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Free Radical Biology and Medicine
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
28
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
64-74
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extension of life-span by introduction of telomerase into normal human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of telomere length by the human telomeric protein TRF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal human chromosomes have long G-rich telomeric overhangs at one end
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low oxygen concentration extends the lifespan of cultured human diploid cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of oxygen and vitamin E on the lifespan of human diploid cells in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accelerated telomere shortening in fibroblasts after extended periods of confluency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-regulated generation of single-stranded G-rich DNA in the absence of telomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The terminal DNA structure of mammalian chromosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial water loss and aging of cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similar gene expression pattern in senescent and hyperoxic-treated fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flow cytometric detection of hydrogen peroxide production induced by doxorubicin in cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a critical telomere length in senescent human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian telomeres end in a large duplex loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900207-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0891-5849(99)00207-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
10656292
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10656292
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10656292%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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