(Q52672671)

English

Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment.

scientific article published on 26 September 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

Ali Shilatifard

2

object named as

Ali Shilatifard

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

author name string

Joel C Eissenberg

1

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

Nikolay Dorokhov

3

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

Dorian E Michener

4

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

publication date

26 September 2006

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

Molecular Genetics and Genomics

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

277

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

2

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

101-114

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

https://scigraph.springernature.com/pub.10.1007/s00438-006-0164-2

0 references

Transcriptional elongation control by RNA polymerase II: a new frontier

1 reference

https://api.crossref.org/works/10.1007%2FS00438-006-0164-2

21 January 2018

DNA-binding and chromatin localization properties of CHD1

1 reference

https://api.crossref.org/works/10.1007%2FS00438-006-0164-2

21 January 2018

Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNAi triggered by symmetrically transcribed transgenes in Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide survey of protein kinases required for cell cycle progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein traffic on the heat shock promoter: parking, stalling, and trucking along

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription elongation factor hSPT5 stimulates mRNA capping

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-nucleosome mapping of histone modifications in S. cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tails of intrigue: phosphorylation of RNA polymerase II mediates histone methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavopiridol inhibits P-TEFb and blocks HIV-1 replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA polymerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elongation by RNA polymerase II: the short and long of it

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bur1 kinase is required for efficient transcription elongation by RNA polymerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the RNA polymerase II carboxy-terminal domain by the Bur1 cyclin-dependent kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drosophila ELL is associated with actively elongating RNA polymerase II on transcriptionally active sites in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activity of positive transcription elongation factor b kinase in vivo requires the C-terminal domain of RNA polymerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

dELL is an essential RNA polymerase II elongation factor with a general role in development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of histone H3 lysine 36 is required for normal development in Neurospora crassa

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrating mRNA processing with transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic interactions of Spt4-Spt5 and TFIIS with the RNA polymerase II CTD and CTD modifying enzymes in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional elongation by RNA polymerase II and histone methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-TEFb kinase recruitment and function at heat shock loci

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double chromodomains cooperate to recognize the methylated histone H3 tail

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional genomic analysis of cell morphology using RNA interference

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHD1 is concentrated in interbands and puffed regions of Drosophila polytene chromosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/17001490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00438-006-0164-2

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 May 2018

http://europepmc.org/abstract/MED/17001490

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