(Q5247052)

English

death-inducing signaling complex

A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activatio

  • GO:0031264
  • death receptor-induced signalling complex
  • death-inducing signalling complex
  • DISC
  • death receptor-induced signaling complex
  • DISC protein complex
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