(Q50335551)

5 March 2018

http://europepmc.org/abstract/MED/16186825

title

Essential function for the kinase TAK1 in innate and adaptive immune responses. (English)

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

4

Jun Ninomiya-Tsuji

1 reference

5 March 2018

Shintaro Sato

1

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5 March 2018

http://europepmc.org/abstract/MED/16186825

Hideki Sanjo

2

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Kiyoshi Takeda

3

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Masahiro Yamamoto

5

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Taro Kawai

6

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Kunihiro Matsumoto

7

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Osamu Takeuchi

8

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

Shizuo Akira

9

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

language of work or name

English

0 references

publication date

25 September 2005

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

published in

Nature Immunology

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5 March 2018

http://europepmc.org/abstract/MED/16186825

volume

6

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5 March 2018

http://europepmc.org/abstract/MED/16186825

issue

11

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5 March 2018

http://europepmc.org/abstract/MED/16186825

page(s)

1087-1095

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5 March 2018

http://europepmc.org/abstract/MED/16186825

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

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TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages

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TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

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Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

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TAB3, a new binding partner of the protein kinase TAK1

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TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

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Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis

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IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

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The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

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Role of different B-cell subsets in the specific and polyclonal immune response to T-independent antigens type 2

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7 January 2021

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

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7 January 2021

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

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7 January 2021

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7 January 2021

Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/NI1255

1 reference

5 March 2018

http://europepmc.org/abstract/MED/16186825

1 reference

5 March 2018