Wikidata

(Q4802695)

English

Aryl hydrocarbon receptor nuclear translocator

mammalian protein found in Homo sapiens

  • dioxin receptor, nuclear translocator
  • Hypoxia-inducible factor 1-beta
  • HIF1-beta
  • hypoxia-inducible factor 1, beta subunit
  • class E basic helix-loop-helix protein 2
  • aryl hydrocarbon receptor nuclear translocator
  • bHLHe2
  • ARNT
  • HIF-1-beta
In more languages

Statements

molecular function
protein binding
determination method
IPI
13 references
retrieved
8 April 2019
stated in
Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex
GOA
curator
UniProt
UniProt protein ID
P27540
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization
GOA
curator
UniProt
UniProt protein ID
P27540
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Network organization of the human autophagy system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Artificial ligand binding within the HIF2  PAS-B domain of the HIF2 transcription factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Cbx4 governs HIF-1α to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
retrieved
8 April 2019
stated in
Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IPI
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IDA
ISA
ISM
NAS
5 references
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
NAS
retrieved
8 April 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
ISM
retrieved
8 April 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
ISA
retrieved
8 April 2019
stated in
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IDA
retrieved
8 April 2019
stated in
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27540
determination method
IDA
cell component
biological process
Gene Atlas image
PBB GE ARNT 218221 at fs.png
732 × 530; 12 KB
0 references

Identifiers

MeSH descriptor ID
D051784
subject named as
Aryl Hydrocarbon Receptor Nuclear Translocator
0 references
RefSeq protein ID
PDB structure ID
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q4802695&oldid=2134960205"