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Long Noncoding RNA in Cancer: Wiring Signaling Circuitry
scientific article published on 20 December 2017
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Europe PubMed Central
PubMed publication ID
29274663
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12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
review article
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Europe PubMed Central
title
Long Noncoding RNA in Cancer: Wiring Signaling Circuitry
(English)
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stated in
Europe PubMed Central
PubMed publication ID
29274663
retrieved
12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
author name string
Chunru Lin
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1
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Europe PubMed Central
PubMed publication ID
29274663
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12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
Liuqing Yang
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2
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Europe PubMed Central
PubMed publication ID
29274663
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12 January 2018
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http://europepmc.org/abstract/MED/29274663
publication date
20 December 2017
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Europe PubMed Central
PubMed publication ID
29274663
retrieved
12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
published in
Trends in Cell Biology
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Europe PubMed Central
PubMed publication ID
29274663
retrieved
12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
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2 November 2018
First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer.
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PubMed Central
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2 November 2018
Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer
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PubMed Central
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2 November 2018
Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment
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PubMed Central
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2 November 2018
Recent developments in nanoparticle-based siRNA delivery for cancer therapy
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PubMed Central
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2 November 2018
Protein-coding genes and long noncoding RNAs are differentially expressed in dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib
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PubMed Central
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2 November 2018
Long noncoding RNAs and the genetics of cancer.
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PubMed Central
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2 November 2018
Capture hybridization analysis of RNA targets (CHART).
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PubMed Central
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2 November 2018
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Structural and Functional Characterization of the Kindlin-1 Pleckstrin Homology Domain
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Genome-wide analysis of human SNPs at long intergenic noncoding RNAs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
GENCODE: the reference human genome annotation for The ENCODE Project
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Chromatin isolation by RNA purification (ChIRP).
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PubMed Central
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2 November 2018
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Suppression of progenitor differentiation requires the long noncoding RNA ANCR.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
The genomic binding sites of a noncoding RNA.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
The emergence of lncRNAs in cancer biology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Human polymorphisms at long non-coding RNAs (lncRNAs) and association with prostate cancer risk
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
The novel antisense Bcl-2 inhibitor SPC2996 causes rapid leukemic cell clearance and immune activation in chronic lymphocytic leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Locked nucleic acids (LNAs) reveal sequence requirements and kinetics of Xist RNA localization to the X chromosome
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Large non-coding RNAs: missing links in cancer?
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Targeting p70S6K prevented lung metastasis in a breast cancer xenograft model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
The landscape of somatic copy-number alteration across human cancers
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Nanomedicine based approaches for the delivery of siRNA in cancer
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
RNA and DNA interactions with zwitterionic and charged lipid membranes - a DSC and QCM-D study
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Origins and Mechanisms of miRNAs and siRNAs
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Staufen1 regulates diverse classes of mammalian transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Functional screen for genes responsible for tamoxifen resistance in human breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Antisense oligonucleotides: from design to therapeutic application
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Design of LNA probes that improve mismatch discrimination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Hairpin RNA: a secondary structure of primary importance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Synthesis and properties of a novel bridged nucleic acid analogue, 5'-amino-3',5'-BNA.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Antisense oligonucleotide-based therapeutics for cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Binding of phosphorothioate oligonucleotides to zwitterionic liposomes
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
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2 November 2018
Non–coding RNA genes and the modern RNA world
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Specific binding of the C-terminal Src homology 2 domain of the p85alpha subunit of phosphoinositide 3-kinase to phosphatidylinositol 3,4,5-trisphosphate. Localization and engineering of the phosphoinositide-binding motif
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: unexpected functions for ancient enzymes?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Crystal structure of the ribonucleoprotein core of the signal recognition particle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
RNAs that bind and change the permeability of phospholipid membranes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Akt activation by growth factors is a multiple-step process: the role of the PH domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Structure, interactions and dynamics of PRD1 virus II. Organization of the viral membrane and DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5869122
retrieved
2 November 2018
Conformation of the TAR RNA-Arginine Complex by NMR Spectroscopy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A mouse locus at which transcription from both DNA strands produces mRNAs complementary at their 3′ ends
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differential scanning calorimetry study on the binding of nucleic acids to dimyristoylphosphatidylcholine-sphingosine liposomes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The first analogues of LNA (Locked Nucleic Acids): Phosphorothioate-LNA and 2′-thio-LNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A Structural Basis for RNAminus signLigand Interactions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DUF283 domain of Dicer proteins has a double-stranded RNA-binding fold
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Paraneoplastic thrombocytosis in ovarian cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29274663
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TCB.2017.11.008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
29274663
retrieved
12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
PMC publication ID
5869122
0 references
PubMed publication ID
29274663
1 reference
stated in
Europe PubMed Central
PubMed publication ID
29274663
retrieved
12 January 2018
reference URL
http://europepmc.org/abstract/MED/29274663
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