(Q45764676)

English

Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respiratory syncytial virus vaccine candidate results from the acquisition of a single mutation in the polymerase (L) gene

scientific article published in January 1996

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scholarly article

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Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

Acquisition of the ts phenotype by a chemically mutagenized cold-passaged human respiratory syncytial virus vaccine candidate results from the acquisition of a single mutation in the polymerase (L) gene (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

1 reference

based on heuristic

inferred from title

respiratory syncytial virus

object named as

human respiratory syncytial virus

1 reference

based on heuristic

inferred from title

James E. Crowe, Jr.

1

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

Cai-Yen Firestone

2

object named as

C Y Firestone

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

Brian R. Murphy

5

object named as

B R Murphy

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

author name string

S S Whitehead

3

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

P L Collins

4

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

publication date

1 January 1996

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Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

13

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Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

3

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

269-273

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: I. Viral shedding, immunologic response, and associated illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for va

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respiratory syncytial virus (RSV) temperature-sensitive mutant vaccines and vaccinia virus recombinants that express the surface glycoproteins of RSV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: II. Genetic analysis of virus recovered during infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide sequences of the 3′ leader and 5′ trailer regions of human respiratory syncytial virus genomic RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rescue of synthetic analogs of respiratory syncytial virus genomic RNA and effect of truncations and mutations on the expression of a foreign reporter gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Satisfactorily attenuated and protective mutants derived from a partially attenuated cold-passaged respiratory syncytial virus mutant by introduction of additional attenuating mutations during chemical mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complete nucleotide sequence of two cold-adapted, temperature-sensitive attenuated mutant vaccine viruses (cp12 and cp45) derived from the JS strain of human parainfluenza virus type 3 (PIV3).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of a highly attenuated, live respiratory syncytial virus vaccine to adults and children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of a temperature-sensitive mutant of respiratory syncytial virus in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The attenuation phenotype conferred by the M gene of the influenza A/Ann Arbor/6/60 cold-adapted virus (H2N2) on the A/Korea/82 (H3N2) reassortant virus results from a gene constellation effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A further attenuated derivative of a cold-passaged temperature-sensitive mutant of human respiratory syncytial virus retains immunogenicity and protective efficacy against wild-type challenge in seronegative chimpanzees

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-Temperature-Grown RS Virus in Adult Volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence analysis of the polymerase L gene of human respiratory syncytial virus and predicted phylogeny of nonsegmented negative-strand viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cold-passaged, attenuated strain of human respiratory syncytial virus contains mutations in the F and L genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and immunological response of infants and children to administration of low-temperature adapted respiratory syncytial virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cold-passaged, temperature-sensitive mutants of human respiratory syncytial virus (RSV) are highly attenuated, immunogenic, and protective in seronegative chimpanzees, even when RSV antibodies are infused shortly before immunization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9035372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00366988

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 December 2017

http://europepmc.org/abstract/MED/9035372

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