(Q45151645)

English

Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors

scientific article published on 15 November 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

author name string

Toshifumi Sugatani

1

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Keith A Hruska

2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

language of work or name

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publication date

15 November 2004

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

10 December 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

3583-3589

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

The extracellular matrix as a cell survival factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Osteoclast differentiation and activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Signal transduction by receptor activator of nuclear factor kappa B in osteoclasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Activin A stimulates IkappaB-alpha/NFkappaB and RANK expression for osteoclast differentiation, but not AKT survival pathway in osteoclast precursors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

M-CSF, TNFα and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Mammalian target of rapamycin inhibition as therapy for hematologic malignancies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Interleukin 3-dependent survival by the Akt protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410480200

21 January 2018

Identifiers

10.1074/JBC.M410480200

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

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