(Q45113910)

9 December 2017

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title

Biology of the interleukin-2 receptor (English)

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9 December 2017

0 references

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Nelson BH

1

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9 December 2017

Willerford DM

series ordinal

2

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9 December 2017

publication date

1 January 1998

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9 December 2017

published in

Advances in Immunology

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9 December 2017

volume

70

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9 December 2017

page(s)

1-81

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Die and let live: eliminating dangerous lymphocytes

9 December 2017

cites work

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7 January 2021

Immunopharmacology of rapamycin

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7 January 2021

Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain

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7 January 2021

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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7 January 2021

Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

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7 January 2021

Fas ligand mediates activation-induced cell death in human T lymphocytes

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7 January 2021

Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes

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7 January 2021

Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling

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7 January 2021

Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways

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7 January 2021

Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75

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7 January 2021

Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation

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7 January 2021

Interleukin-2 (IL-2)-mediated induction of the IL-2 receptor alpha chain gene. Critical role of two functionally redundant tyrosine residues in the IL-2 receptor beta chain cytoplasmic domain and suggestion that these residues mediate more than Stat

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7 January 2021

Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes

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7 January 2021

Ligand binding kinetics of IL-2 and IL-15 to heteromers formed by extracellular domains of the three IL-2 receptor subunits

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7 January 2021

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

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7 January 2021

Isolation of interleukin 2-induced immediate-early genes

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7 January 2021

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.

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7 January 2021

Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells.

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7 January 2021

Human B lymphocytes express the p75 component of the interleukin 2 receptor

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7 January 2021

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

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7 January 2021

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

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7 January 2021

A model system for peptide hormone action in differentiation: interleukin 2 induces a B lymphoma to transcribe the J chain gene

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7 January 2021

Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle.

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7 January 2021

Mechanism of V(D)J recombination

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7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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7 January 2021

Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division

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7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

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7 January 2021

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

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7 January 2021

Mouse CD1 is distinct from and co-exists with TL in the same thymus

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7 January 2021

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

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7 January 2021

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

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7 January 2021

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

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7 January 2021

Protein-tyrosine kinase-dependent activation of STAT transcription factors in interleukin-2- or interleukin-4-stimulated T lymphocytes

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7 January 2021

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

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7 January 2021

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

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7 January 2021

Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants

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7 January 2021

A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6.

1 reference

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7 January 2021

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 reference

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7 January 2021

IL-7 receptor and VDJ recombination: trophic versus mechanistic actions

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7 January 2021

Transient expression of interleukin 2 receptors. Consequences for T cell growth

1 reference

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7 January 2021

The interleukin-2 T-cell system: a new cell growth model.

1 reference

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7 January 2021

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression

1 reference

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7 January 2021

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

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7 January 2021

Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes

1 reference

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7 January 2021

A potential role for interleukin-15 in the regulation of human natural killer cell survival

1 reference

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7 January 2021

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

1 reference

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7 January 2021

Bcl-XL and Bcl-2 repress a common pathway of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes.

1 reference

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7 January 2021

Interleukin 7 is a T-cell growth factor

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7 January 2021

IL-2 receptor alpha chain expression during early B lymphocyte differentiation

1 reference

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7 January 2021

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals

1 reference

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7 January 2021

Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.

1 reference

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7 January 2021

Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis

1 reference

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7 January 2021

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

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7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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7 January 2021

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

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7 January 2021

Molecular approaches to analysis of X-linked immunodeficiencies

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7 January 2021

Nonrandom X chromosome inactivation in B cells from carriers of X chromosome-linked severe combined immunodeficiency

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7 January 2021

Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor alpha chain required for growth signal transduction

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7 January 2021

Cloning, sequence and expression of human interleukin-2 receptor

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7 January 2021

Contingent genetic regulatory events in T lymphocyte activation

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7 January 2021

T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation.

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7 January 2021

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

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7 January 2021

A transgenic T cell receptor restores thymocyte differentiation in interleukin-7 receptor alpha chain-deficient mice

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7 January 2021

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

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7 January 2021

STATs and gene regulation

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7 January 2021

Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-q13.

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7 January 2021

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

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7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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7 January 2021

Cytokines: shared receptors, distinct functions.

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7 January 2021

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

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7 January 2021

Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection

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7 January 2021

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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7 January 2021

Cellular and genetic analyses of IL-2 production and IL-2 receptor expression in a patient with familial T-cell-dominant immunodeficiency

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7 January 2021

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

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7 January 2021

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

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7 January 2021

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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7 January 2021

Expression of interleukin-2 receptor γ on human monocytes: characterization of lineage specific post-translational modifications

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7 January 2021

Expression and role of p75 interleukin 2 receptor on human monocytes

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7 January 2021

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

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7 January 2021

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

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7 January 2021

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes

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7 January 2021

Naturally occurring primary deficiencies of the immune system

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7 January 2021

Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1 reference

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7 January 2021

Interleukin 2 signaling involves the phosphorylation of Stat proteins

1 reference

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity

1 reference

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7 January 2021

Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Recent advances in understanding V(D)J recombination.

1 reference

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7 January 2021

In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Long term culture of tumour-specific cytotoxic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin 2 activates STAT5 transcription factor (mammary gland factor) and specific gene expression in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Control points in early T-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Intermediate Affinity Interleukin-2 Receptor Mediates Survival via a Phosphatidylinositol 3-Kinase-dependent Pathway

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7 January 2021

Self-tolerance checkpoints in B lymphocyte development

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7 January 2021

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The interleukin 2 receptor (IL-2R): the IL-2R alpha subunit alters the function of the IL-2R beta subunit to enhance IL-2 binding and signaling by mechanisms that do not require binding of IL-2 to IL-2R alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Activation-induced apoptosis in lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

1 reference

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7 January 2021

Analysis of T-cell subpopulations in human IL-2R alpha transgenic mice: expansion of Thy1.2- thymocytes and depletion of double-positive T-cell precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Cell cycle control and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Dimerization of cell surface receptors in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Molecular cloning and expression of an IL-6 signal transducer, gp130

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Identification and purification of human Stat proteins activated in response to interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

B cell growth and differentiation factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Janus kinases in cytokine signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Cytokine receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Effects of the deregulated expression of human interleukin-2 in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin (IL)-2 activation of p21ras in murine myeloid cells transfected with human IL-2 receptor β chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Mitogenic signaling and inhibition of apoptosis via the erythropoietin receptor Box-1 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Peripheral clonal elimination of functional T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Detection and functional studies of p60-65 (Tac antigen) on activated human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

An alternative to SH2 domains for binding tyrosine-phosphorylated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Two Discrete Regions of Interleukin-2 (IL2) Receptor β Independently Mediate IL2 Activation of a PD98059/Rapamycin/Wortmannin-insensitive Stat5a/b Serine Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Expression of the mouse interleukin-2 receptor gamma chain in various cell populations of the thymus and spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Thymic selection and peptide-induced activation of T cell receptor-transgenic CD8 T cells in interleukin-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Immunological self-tolerance: an analysis employing cytokines or cytokine receptors encoded by transgenes or a recombinant vaccinia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Immune responses in interleukin-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Sounding the alarm: protein kinase cascades activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

p70s6k function is essential for G1 progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Delineation of an enhancerlike positive regulatory element in the interleukin-2 receptor alpha-chain gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Characterization of the human interleukin-2 receptor beta-chain gene promoter: regulation of promoter activity by ets gene products

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The immediate-early gene product Egr-1 regulates the human interleukin-2 receptor beta-chain promoter through noncanonical Egr and Sp1 binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukins 4 and 5 control expression of IL-2 receptor on murine B cells through independent induction of its two chains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Bclx regulates the survival of double-positive thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Clonal expansion precedes anergy and death of V beta 8+ peripheral T cells responding to staphylococcal enterotoxin B in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Kinetic study of interleukin-2 binding on the reconstituted interleukin-2 receptor complexes including the human gamma chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor beta chain (IL-2R beta).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Signal transduction by interleukin 2 receptor beta chain: importance of the structural integrity as revealed by site-directed mutagenesis and generation of chimeric receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The cis-acting elements controlling mouse IL-2R alpha transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Fas and Fas ligand: a death factor and its receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Probing a role of subunit IV of the Escherichia coli bo-type ubiquinol oxidase by deletion and cross-linking analyses.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Ig RNA expression in normal B cells stimulated with anti-IgM antibody and T cell-derived growth and differentiation factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Stimulation of B-cell progenitors by cloned murine interleukin-7

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960386-7

7 January 2021

Molecular cloning of cDNA encoding human interleukin-2 receptor

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7 January 2021

Expression of functional interleukin-2 receptors in human light chain/Tac ransgenic mice

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7 January 2021

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

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7 January 2021

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain

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7 January 2021

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

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7 January 2021

Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation

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7 January 2021

Defective lymphoid development in mice lacking Jak3

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7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

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7 January 2021

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

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7 January 2021

Functional analysis of the human interleukin 2 receptor gamma chain gene promoter

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7 January 2021

Recombinant interleukin 2 therapy in severe combined immunodeficiency disease

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7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

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7 January 2021

Protein modules and signalling networks

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7 January 2021

Interleukin 2 activates extracellular signal-regulated protein kinase 2.

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7 January 2021

Gamma chain-associated cytokine receptors signal through distinct transducing factors

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7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

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7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

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7 January 2021

Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells

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7 January 2021

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

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7 January 2021

The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1.

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7 January 2021

Interleukin 2 mediates p72 syk activation in peripheral blood lymphocytes

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7 January 2021

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

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7 January 2021

Social controls on cell survival and cell death

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7 January 2021

Expression and function of interleukin-2 receptors on immature thymocytes.

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7 January 2021

Recognition events that inhibit and activate natural killer cells

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7 January 2021

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

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7 January 2021

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

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7 January 2021

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

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7 January 2021

Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo

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7 January 2021

Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

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7 January 2021

T cell growth factor receptors. Quantitation, specificity, and biological relevance

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7 January 2021

Peripheral selection of the T cell repertoire

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7 January 2021

A population of early fetal thymocytes expressing Fc gamma RII/III contains precursors of T lymphocytes and natural killer cells

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7 January 2021

Cooperative interactions between the interleukin 2 receptor alpha and beta chains alter the interleukin 2-binding affinity of the receptor subunits

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7 January 2021

IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development

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7 January 2021

The primary immunodeficiencies

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7 January 2021

The development of functionally responsive T cells

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7 January 2021

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

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7 January 2021

Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells

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7 January 2021

Receptor-stimulated death pathway is opened by antigen in mature T cells

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7 January 2021

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

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7 January 2021

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

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7 January 2021

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

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7 January 2021

Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4

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7 January 2021

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

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7 January 2021

Crucial role of Jak3 in negative selection of self-reactive T cells.

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7 January 2021

Identification of a common T/natural killer cell progenitor in human fetal thymus.

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7 January 2021

Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4

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7 January 2021

Localization in human interleukin 2 of the binding site to the alpha chain (p55) of the interleukin 2 receptor

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7 January 2021

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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7 January 2021

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

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7 January 2021

A cell culture model for T lymphocyte clonal anergy

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7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

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7 January 2021

Elf-1 contributes to the function of the complex interleukin (IL)-2-responsive enhancer in the mouse IL-2 receptor alpha gene

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7 January 2021

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

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7 January 2021

An interleukin-2 receptor gamma chain mutation with normal thymus morphology

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7 January 2021

A 100-kilodalton protein is associated with the murine interleukin 2 receptor: biochemical evidence that p100 is distinct from the alpha and beta chains

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7 January 2021

The influence of the MAPK pathway on T cell lineage commitment

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7 January 2021

G1 phase progression: cycling on cue

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7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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7 January 2021

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

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7 January 2021

The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment

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7 January 2021

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc

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7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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7 January 2021

Early T lymphocyte progenitors

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7 January 2021

The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activities

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7 January 2021

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

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7 January 2021

Apoptosis, Fas and systemic autoimmunity: the MRL-lpr/lpr model

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7 January 2021

Interleukin-2: inception, impact, and implications

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7 January 2021

Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells

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7 January 2021

Mouse interleukin-2 receptor alpha gene expression. Delimitation of cis-acting regulatory elements in transgenic mice and by mapping of DNase-I hypersensitive sites.

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7 January 2021

Interleukin 3-dependent survival by the Akt protein kinase

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7 January 2021

Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytesin vivo

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7 January 2021

Mouse interleukin-2 receptor alpha gene expression. Interleukin-1 and interleukin-2 control transcription via distinct cis-acting elements

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7 January 2021

Lymphocyte life-span and memory

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients

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7 January 2021

Interleukin-2 induction of T-cell G1 progression and c-myb expression

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7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

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7 January 2021

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

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7 January 2021

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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7 January 2021

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

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7 January 2021

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

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7 January 2021

Role of IRS-2 in insulin and cytokine signalling

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7 January 2021

Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain

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7 January 2021

Normal thymic selection, superantigen-induced deletion and Fas-mediated apoptosis of T cells in IL-2 receptor beta chain-deficient mice

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7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

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7 January 2021

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

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7 January 2021

IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels

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7 January 2021

ICE-related proteases in apoptosis.

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7 January 2021

A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction

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7 January 2021

Essential role of Stat6 in IL-4 signalling

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7 January 2021

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

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7 January 2021

Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM

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7 January 2021

STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

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7 January 2021

Cloning of the gamma chain of the human IL-2 receptor

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7 January 2021

An associated molecule, p64, with high-affinity interleukin 2 receptor

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7 January 2021

Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.

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7 January 2021

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

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7 January 2021

Peripheral selection of T cell repertoires: the role of continuous thymus output

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7 January 2021

Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivo

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7 January 2021

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

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7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

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7 January 2021

Peripheral expression of Jak3 is required to maintain T lymphocyte function

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7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

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7 January 2021

Involvement of the interleukin 2 pathway in the rearrangement and expression of both alpha/beta and gamma/delta T cell receptor genes in human T cell precursors

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7 January 2021

lnterleukin-2-dependent autocrine proliferation in T-cell development

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7 January 2021

Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line

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7 January 2021

Biology of natural killer cells

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7 January 2021

The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells

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7 January 2021

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies

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7 January 2021

Expression of Tac antigen on activated normal human B cells

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7 January 2021

Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line

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7 January 2021

Signal transduction by receptors with tyrosine kinase activity

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7 January 2021

Toward an understanding of the molecular mechanisms of physiological cell death.

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7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

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7 January 2021

Identification of a direct interaction between interleukin 2 and the p64 interleukin 2 receptor gamma chain

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7 January 2021

Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R

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7 January 2021

The multi-subunit interleukin-2 receptor

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7 January 2021

Expression of interleukin 2 receptors on activated human B cells

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7 January 2021

The interleukin 2 receptor. Functional consequences of its bimolecular structure

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7 January 2021

Induction of sensitivity to activation-induced death in primary CD4+ cells: a role for interleukin-2 in the negative regulation of responses by mature CD4+ T cells

1 reference

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7 January 2021

Characterization of cis-regulatory elements of the c-myc promoter responding to human GM-CSF or mouse interleukin 3 in mouse proB cell line BA/F3 cells expressing the human GM-CSF receptor

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7 January 2021

Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity

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7 January 2021

Severe combined immunodeficiency due to a specific defect in the production of interleukin-2

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7 January 2021

Life, death, and the pursuit of apoptosis.

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7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

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7 January 2021

Developmental regulation of V(D)J recombination and lymphocyte differentiation

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7 January 2021

Generation of lytic natural killer 1.1+, Ly-49- cells from multipotential murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates

1 reference

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7 January 2021

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

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7 January 2021

T cell receptor signals enhance susceptibility to Fas-mediated apoptosis

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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7 January 2021

Induction of apoptosis in mature T cells by tumour necrosis factor

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7 January 2021

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1 reference

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7 January 2021

Are the IL-2 receptors expressed in the murine fetal thymus functional?

1 reference

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7 January 2021

10.1016/S0065-2776(08)60386-7

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