(Q44990091)

8 December 2017

title

Cooperative effects of mutations in a recombinant Fab on the kinetics of antigen binding (English)

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8 December 2017

Rauffer-Bruyre N

1

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8 December 2017

Chatellier J

2

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8 December 2017

Weiss E

3

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8 December 2017

Van Regenmortel MH

4

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8 December 2017

Altschuh D

5

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8 December 2017

language of work or name

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1 February 1997

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8 December 2017

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8 December 2017

volume

34

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8 December 2017

issue

2

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8 December 2017

page(s)

165-173

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Effects of site-specific amino acid modification on protein interactions and biological function

8 December 2017

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Stepwise improvements in catalytic effectiveness: independence and interdependence in combinations of point mutations of a sluggish triosephosphate isomerase.

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Functional mapping of conserved residues located at the VL and VH domain interface of a Fab

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Comparative interaction kinetics of two recombinant Fabs and of the corresponding antibodies directed to the coat protein of tobacco mosaic virus

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SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange

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Antibody framework residues affecting the conformation of the hypervariable loops

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7 January 2021

Antigen-antibody binding and mass transport by convection and diffusion to a surface: a two-dimensional computer model of binding and dissociation kinetics.

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Patterns of nonadditivity between pairs of stability mutations in staphylococcal nuclease

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Non-additivity in protein-protein interactions

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Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins

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Analysis of the Factor VIIa Binding Site on Human Tissue Factor: Effects of Tissue Factor Mutations on the Kinetics and Thermodynamics of Binding

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Direct and indirect pathways of functional coupling in human hemoglobin are revealed by quantitative low-temperature isoelectric focusing of mutant hybrids

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Affinity maturation of human growth hormone by monovalent phage display

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Functional Linkage Between the Active Site of α-Lytic Protease and Distant Regions of Structure: Scanning Alanine Mutagenesis of a Surface Loop Affects Activity and Substrate Specificity

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7 January 2021

Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods.

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7 January 2021

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7 January 2021

Molecular modeling and site-directed rautagenesis of an anti-phosphotyrosine antibody predicts the combining site and allows the detection of higher affinity interactions

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Affinity maturation of a high-affinity human monoclonal antibody against the third hypervariable loop of human immunodeficiency virus: use of phage display to improve affinity and broaden strain reactivity

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7 January 2021

Additivity of mutational effects in proteins

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7 January 2021

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7 January 2021

Framework residues 71 and 93 of the chimeric B72.3 antibody are major determinants of the conformation of heavy-chain hypervariable loops

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7 January 2021

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

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Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA.

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7 January 2021

10.1016/S0161-5890(97)00003-5

Identifiers

DOI

1 reference

8 December 2017

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