(Q44523640)

3 December 2017

title

Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation (English)

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3 December 2017

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3

Harvey J Clewell

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3 December 2017

P Robinan Gentry

1

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3 December 2017

Tammie R Covington

series ordinal

2

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3 December 2017

language of work or name

English

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publication date

1 August 2003

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Regulatory Toxicology and Pharmacology

3 December 2017

published in

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3 December 2017

volume

38

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3 December 2017

issue

1

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3 December 2017

page(s)

1-16

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Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.

3 December 2017

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7 January 2021

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

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7 January 2021

A computer program linking physiologically based pharmacokinetic model with cancer risk assessment for breast-fed infants

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Pharmacokinetics of toxic chemicals in breast milk: use of PBPK models to predict infant exposure

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7 January 2021

Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone

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7 January 2021

Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model.

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7 January 2021

Review and evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry

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7 January 2021

Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.

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7 January 2021

Lactational transfer of volatile chemicals in breast milk

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7 January 2021

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE)

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7 January 2021

Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration

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7 January 2021

A physiologically based pharmacokinetic model for methyl mercury in the pregnant rat and fetus

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7 January 2021

Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and suckling pups

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7 January 2021

A physiologically based pharmacokinetic computer model for human pregnancy.

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7 January 2021

In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human

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7 January 2021

An in vitro method for determination of tissue partition coefficients of non-volatile chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin and estradiol.

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7 January 2021

Tissue and species differences in enzymes of epoxide metabolism

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7 January 2021

Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds

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7 January 2021

Development of Alcohol Dehydrogenase Activity in the Human Liver

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7 January 2021

An analysis of the need for an additional uncertainty factor for infants and children

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7 January 2021

A physiologically based pharmacokinetic model for nicotine and cotinine in man

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7 January 2021

A Risk Assessment Approach for Nursing Infants Exposed to Volatile Organics through the Mother's Occupational Inhalation Exposure

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7 January 2021

Delayed ontogenesis of CYP1A2 in the human liver

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7 January 2021

Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: in-vivo/in-vitro correlation and inducibility.

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7 January 2021

Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period

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7 January 2021

Development of a physiologically based pharmacokinetic model to describe the disposition of methanol in pregnant rats and mice.

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7 January 2021

Physiologically-based pharmacokinetic model for pregnancy as a tool for investigation of developmental mechanisms

1 reference

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7 January 2021

Transplacental and lactational transfer of p,p'-DDE in Sprague-Dawley rats

1 reference

https://api.crossref.org/works/10.1016%2FS0273-2300%2803%2900047-3

7 January 2021

10.1016/S0273-2300(03)00047-3

Identifiers

DOI

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3 December 2017

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