(Q44482174)

3 December 2017

title

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts (English)

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3 December 2017

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Nandini Kishore

1

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3 December 2017

Cindy Sommers

2

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3 December 2017

Sumathy Mathialagan

3

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3 December 2017

Julia Guzova

4

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3 December 2017

Min Yao

5

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3 December 2017

Scott Hauser

6

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3 December 2017

Khai Huynh

7

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3 December 2017

Sheri Bonar

8

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3 December 2017

Cindy Mielke

9

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3 December 2017

Lee Albee

10

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3 December 2017

Richard Weier

11

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3 December 2017

Matthew Graneto

12

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3 December 2017

Cathleen Hanau

13

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3 December 2017

Thao Perry

14

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3 December 2017

Catherine S Tripp

15

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3 December 2017

language of work or name

English

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publication date

17 June 2003

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Journal of Biological Chemistry

3 December 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

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3 December 2017

volume

278

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3 December 2017

issue

35

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3 December 2017

page(s)

32861-32871

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

3 December 2017

cites work

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NF-kappaB at the crossroads of life and death

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

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In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

21 January 2018

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Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

21 January 2018

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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

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Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

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Missing pieces in the NF-kappaB puzzle

21 January 2018

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I kappa B-independent control of NF-kappa B activity by modulatory phosphorylations

21 January 2018

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Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

21 January 2018

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A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes

21 January 2018

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An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

21 January 2018

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IkappaB family members function by different mechanisms

21 January 2018

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The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

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Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

21 January 2018

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

21 January 2018

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Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

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IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

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Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

21 January 2018

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Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis

21 January 2018

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit.

21 January 2018

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Transcriptional activation by NF-kappaB requires multiple coactivators

21 January 2018

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

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NAK is an IkappaB kinase-activating kinase

21 January 2018

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NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M211439200

1 reference

3 December 2017

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