(Q44340159)

2 December 2017

title

Allosteric regulation of the transcription factor NFAT1 by multiple phosphorylation sites: a mathematical analysis (English)

1 reference

2 December 2017

0 references

2

1 reference

2 December 2017

Carlos Salazar

1

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

Journal of Molecular Biology

2 December 2017

number of pages

15

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

2 December 2017

volume

327

1 reference

2 December 2017

issue

1

1 reference

2 December 2017

page(s)

31-45

1 reference

The regulation of protein function by multisite phosphorylation--a 25 year update

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Two-state allosteric behavior in a single-domain signaling protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Transcription factors of the NFAT family: regulation and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

The role of NF-AT transcription factors in T cell activation and differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Calcium, calcineurin, and the control of transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Manipulating immune responses with immunosuppressive agents that target NFAT.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Regulation of nuclear localization: a key to a door

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Conformational spread in a ring of proteins: a stochastic approach to allostery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Escherichia coli aspartate transcarbamoylase: the molecular basis for a concerted allosteric transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Is cooperative oxygen binding by hemoglobin really understood?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Folding and binding cascades: dynamic landscapes and population shifts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Multi-site phosphorylation of Pho4 by the cyclin-CDK Pho80-Pho85 is semi-processive with site preference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Protein kinase A negatively modulates the nuclear accumulation of NF-ATc1 by priming for subsequent phosphorylation by glycogen synthase kinase-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Ultrasensitivity in the mitogen-activated protein kinase cascade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

An amplified sensitivity arising from covalent modification in biological systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Signaling through calcium, calcineurin, and NF-AT in lymphocyte activation and development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Calcium signaling mechanisms in T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

The activating dual phosphorylation of MAPK by MEK is nonprocessive

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Calcium oscillations increase the efficiency and specificity of gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Response regulator output in bacterial chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Generalization of the theory of transition times in metabolic pathways: a geometrical approach.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

Modelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900085-8

10.1016/S0022-2836(03)00085-8

7 January 2021

Identifiers

DOI

1 reference

2 December 2017

1 reference