(Q42446777)

31 October 2017

title

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells (English)

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chronic lymphocytic leukemia

31 October 2017

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8

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31 October 2017

V Berno

5

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author name string

S Gobessi

1

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31 October 2017

L Laurenti

2

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31 October 2017

P G Longo

3

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31 October 2017

L Carsetti

4

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31 October 2017

S Sica

6

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31 October 2017

G Leone

7

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31 October 2017

publication date

18 December 2008

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31 October 2017

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31 October 2017

volume

23

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31 October 2017

issue

4

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31 October 2017

page(s)

686-697

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Recent advances in the molecular biology and immunobiology of chronic lymphocytic leukemia.

31 October 2017

cites work

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Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma

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A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

21 January 2018

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The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

21 January 2018

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Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness

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TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways

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21 January 2018

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21 January 2018

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21 January 2018

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Immunotoxicity assessment for the novel Spleen tyrosine kinase inhibitor R406.

21 January 2018

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Mechanisms of B-cell lymphoma pathogenesis

21 January 2018

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Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation

21 January 2018

1 reference

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Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia

21 January 2018

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Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status

21 January 2018

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7 January 2021

Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.346

7 January 2021

Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.346

7 January 2021

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.346

7 January 2021

Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.346

7 January 2021

AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.346

7 January 2021

Identifiers

DOI

10.1038/LEU.2008.346

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Dimensions Publication ID

31 October 2017

1030591731

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