(Q42446435)

English

The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.

scientific article published on August 2003

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

P. Jeffrey Conn

9

object named as

P Jeffrey Conn

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

author name string

Gene G Kinney

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Cyrille Sur

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Maryann Burno

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Pierre J Mallorga

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Jacinta B Williams

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

David J Figueroa

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Marion Wittmann

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Wei Lemaire

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

P Jeffrey Conn

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

23

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

7586-7591

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

A.E. Bennett Research Award. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor hypofunction model of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular modulation of NMDA receptor function by antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA-associated glycine binding site increases in schizophrenic brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glycine and structurally related amino acids on generation of long-term potentiation in rat hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine synergistically potentiates the enhancement of LTP induced by a sulfhydryl reducing agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the NMDA receptor/channel antagonists CPP and MK801 on hippocampal field potentials and long-term potentiation in anesthetized rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apomorphine, d-amphetamine, strychnine and yohimbine do not alter prepulse inhibition of the acoustic startle reflex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism of phencyclidine-induced hyperactivity by glycine in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free and conjugated amino acids in human CSF: influence of age and sex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of negative symptoms in schizophrenia by glycine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute administration of typical and atypical antipsychotic drugs induces distinctive patterns of Fos expression in the rat forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free d-aspartate and d-serine in the mammalian brain and periphery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of Phencyclidine-Induced Hyperactivity by Glycine and the Glycine Uptake Inhibitor Glycyldodecylamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics, haloperidol-induced catalepsy and haloperidol-induced changes in acoustic startle and prepulse inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memory and the brain: unexpected chemistries and a new pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-serine added to antipsychotics for the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartate receptor function by glycine transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12930797

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-20-07586.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6740762&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42446435&oldid=1572384331"