(Q42415954)

30 October 2017

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation (English)

1 reference

30 October 2017

0 references

1 reference

1 reference

2

1 reference

30 October 2017

8

Nico van Rooijen

1 reference

Karin Scharffetter-Kochanek

30 October 2017

6

object named as

Karin Scharffetter-Kochanek

1 reference

30 October 2017

Athanasios Stratis

1

1 reference

30 October 2017

Rudolf A Rupec

3

1 reference

30 October 2017

Doreen Markur

4

1 reference

30 October 2017

Karin Hartmann

5

1 reference

30 October 2017

Thorsten Peters

7

1 reference

30 October 2017

Thomas Krieg

9

1 reference

30 October 2017

Ingo Haase

10

1 reference

30 October 2017

language of work or name

English

0 references

publication date

1 August 2006

1 reference

Journal of Clinical Investigation

30 October 2017

1 reference

30 October 2017

116

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30 October 2017

8

1 reference

30 October 2017

2094-2104

1 reference

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

30 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Induction of immunity and inflammation by interleukin-12 family members

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Infliximab induction therapy for patients with severe plaque-type psoriasis: a randomized, double-blind, placebo-controlled trial

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: expression of amphiregulin in the basal epidermis is also associated with synovitis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-kappaB inhibition

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

The many faces of macrophage activation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Inflammatory skin diseases, T cells, and immune surveillance

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Animal models of psoriasis - what can we learn from them?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Spontaneous skin ulceration and defective T cell function in CD18 null mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Transient suppression of macrophage functions by liposome-encapsulated drugs

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Dermal injection of immunocytes induces psoriasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

A subset of macrophages located along the basement membrane ("lining cells") is a characteristic histopathological feature of psoriasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

TNF and the pathology of the skin

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Mast cells and macrophages in early relapsing psoriasis.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

The liposome-mediated macrophage 'suicide' technique

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Cyclosporine for plaque-type psoriasis. Results of a multidose, double-blind trial

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

The therapeutic utility of Interleukin-11 in the treatment of inflammatory disease.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Impairment of neutrophil emigration in CD18-null mice.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

Murine psoriasis-like disorder induced by naive CD4+ T cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525004

A randomized, double-blind, placebo-controlled phase III study evaluating efficacy and tolerability of 2 courses of alefacept in patients with chronic plaque psoriasis

1 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Organization of the monocyte/macrophage system of normal human skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Increased oxidative damage to fibroblasts in skin with and without lesions in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Is psoriasis a T-cell disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Epithelium-lining macrophages in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

In situ localization of CD83-positive dendritic cells in psoriatic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Pathogenic function of IL-1 beta in psoriasiform skin lesions of flaky skin (fsn/fsn) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Resolution of cutaneous inflammation after local elimination of macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Mast cells in the initial stages of psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Immune response in mice that lack the interferon-gamma receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/16886058

1 reference

12 December 2020

Etanercept as monotherapy in patients with psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

IL-4 suppresses IL-1 beta, TNF-alpha and PGE2 production by human peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Inflammatory and immune cell function in psoriasis: II. Monocyte function, lymphokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Involvement of insulin-like growth factor-I in psoriasis as a paracrine growth factor: dermal fibroblasts play a regulatory role in developing psoriatic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16886058

12 December 2020

Identifiers

DOI

10.1172/JCI27179

1 reference

30 October 2017

1 reference

30 October 2017

PubMed publication ID

16886058

1 reference