(Q42245543)

19 October 2017

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. (English)

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19 October 2017

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19 October 2017

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Liliana Schaefer

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19 October 2017

Christina Rebecca Scherbaum

2

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19 October 2017

Murthy Narayana Darisipudi

3

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19 October 2017

Shrikant R Mulay

4

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19 October 2017

Holger Hägele

5

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19 October 2017

Julia Lichtnekert

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19 October 2017

Jan Henrik Hagemann

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19 October 2017

Khader Valli Rupanagudi

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19 October 2017

Mi Ryu

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19 October 2017

Claudia Schwarzenberger

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19 October 2017

Bernd Hohenstein

11

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19 October 2017

Christian Hugo

12

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19 October 2017

Bernd Uhl

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19 October 2017

Christoph A Reichel

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19 October 2017

Fritz Krombach

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19 October 2017

Marc Monestier

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19 October 2017

Helen Liapis

17

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19 October 2017

Kristin Moreth

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19 October 2017

Hans-Joachim Anders

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19 October 2017

7 June 2012

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Journal of the American Society of Nephrology

19 October 2017

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19 October 2017

23

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19 October 2017

8

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19 October 2017

1375-1388

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Mdm2 promotes systemic lupus erythematosus and lupus nephritis

19 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

The nucleosome (histone-DNA complex) is the TLR9-specific immunostimulatory component of Plasmodium falciparum that activates DCs.

26 October 2017

1 reference

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Sepsis and acute kidney injury

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Protein-binding assays in biological liquids using microscale thermophoresis

26 October 2017

1 reference

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HMGB1 Contributes to Kidney Ischemia Reperfusion Injury

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

The sterile inflammatory response

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Extracellular histones are major mediators of death in sepsis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Double-stranded DNA activates glomerular endothelial cells and enhances albumin permeability via a toll-like receptor-independent cytosolic DNA recognition pathway.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

NETs: a new strategy for using old weapons

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Inhibiting glycogen synthase kinase-3 reduces endotoxaemic acute renal failure by down-regulating inflammation and renal cell apoptosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Netting neutrophils in autoimmune small-vessel vasculitis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Potential roles of histones in host defense as antimicrobial agents

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

How dying cells alert the immune system to danger

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

TLR4 activation mediates kidney ischemia/reperfusion injury

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Ischemic acute renal failure: an inflammatory disease?

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Inhibition of Toll-like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Isolation, culture, and characterization of endothelial cells from mouse glomeruli

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

CD14-dependent and CD14-independent signaling pathways in murine macrophages from normal and CD14 knockout mice stimulated with lipopolysaccharide or taxol.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Sepsis: the dark side of histones

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Structure and binding properties of monoclonal antibodies to core histones from autoimmune mice

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402284

Toll-like receptors and danger signaling in kidney injury

17 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

First responders: understanding monocyte-lineage traffic in the acutely injured kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Trif is not required for immune complex glomerulonephritis: dying cells activate mesangial cells via Tlr2/Myd88 rather than Tlr3/Trif

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Postischemic vascular permeability requires both TLR-2 and TLR-4, but only TLR-2 mediates the transendothelial migration of leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22677551

12 December 2020

Identifiers

DOI

10.1681/ASN.2011111077

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

22677551

1 reference