(Q41729181)

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5 November 2019

title

Lck activity controls CD4/CD8 T cell lineage commitment (English)

1 reference

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5 November 2019

1 reference

3

1 reference

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5 November 2019

Jose Alberola-Ila

series ordinal

4

1 reference

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5 November 2019

author name string

G Hernández-Hoyos

series ordinal

1

1 reference

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5 November 2019

S J Sohn

series ordinal

2

1 reference

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5 November 2019

language of work or name

English

0 references

publication date

1 March 2000

1 reference

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5 November 2019

1 reference

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5 November 2019

volume

12

1 reference

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5 November 2019

issue

3

1 reference

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5 November 2019

page(s)

313-322

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Delayed thymocyte development induced by augmented expression of p56lck

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Positive and negative selection invoke distinct signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Exclusion and inclusion of α and β T cell receptor alleles

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Another view of the selective model of thymocyte selection.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Restoration of thymopoiesis in pT alpha-/- mice by anti-CD3epsilon antibody treatment or with transgenes encoding activated Lck or tailless pT alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Positive selection of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

A novel method for measuring CTL and NK cell-mediated cytotoxicity using annexin V and two-color flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

CD8 lineage commitment in the absence of CD8.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

T cells with two functional antigen-specific receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

T cell receptor antagonist peptides induce positive selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Helper T-cell development in the absence of CD4-p56 Ick association

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Regulation of lymphocyte function by protein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Selective events in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

The influence of the MAPK pathway on T cell lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Positive selection of CD4+ T cells by TCR-specific antibodies requires low valency TCR cross-linking: implications for repertoire selection in the thymus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Development of mature CD8+ thymocytes: selection rather than instruction?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

CD4/CD8 lineage commitment: back to instruction?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Precocious expression of T cell functional response genes in vivo in primitive thymocytes before T lineage commitment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980184-3

7 January 2021

10.1016/S1074-7613(00)80184-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10755618%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference