(Q41679375)

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8 November 2019

review article

1 reference

title

Signal transduction by wild-type and leukemogenic Abl proteins (English)

1 reference

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8 November 2019

2

1 reference

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8 November 2019

author name string

A B Raitano

series ordinal

1

1 reference

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8 November 2019

C L Sawyers

series ordinal

3

1 reference

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8 November 2019

publication date

1 December 1997

1 reference

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Biochimica et Biophysica Acta

8 November 2019

published in

1 reference

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8 November 2019

volume

1333

1 reference

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8 November 2019

issue

3

1 reference

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8 November 2019

page(s)

F201-16

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Protein modules and signalling networks

8 November 2019

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The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

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Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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7 January 2021

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

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7 January 2021

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells

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7 January 2021

Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation

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7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

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Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

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7 January 2021

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

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7 January 2021

Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

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7 January 2021

Three distinct signalling responses by murine fibroblasts to genotoxic stress

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7 January 2021

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

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7 January 2021

Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

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7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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7 January 2021

Interaction between ATM protein and c-Abl in response to DNA damage

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7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

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7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

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7 January 2021

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

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7 January 2021

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

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7 January 2021

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

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7 January 2021

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

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7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

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7 January 2021

c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein

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7 January 2021

SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl

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7 January 2021

Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity

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7 January 2021

Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

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7 January 2021

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

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7 January 2021

The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.

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7 January 2021

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

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7 January 2021

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

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7 January 2021

Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

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7 January 2021

Direct demonstration of an intramolecular SH2-phosphotyrosine interaction in the Crk protein

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7 January 2021

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

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7 January 2021

Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II.

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7 January 2021

c-abl has a sequence-specific enhancer binding activity

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7 January 2021

Leukoregulin induction of prostaglandin-endoperoxide H synthase-2 in human orbital fibroblasts. An in vitro model for connective tissue inflammation

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7 January 2021

Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.

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7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts.

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7 January 2021

Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms

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7 January 2021

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase

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7 January 2021

Oncogenic activation of c-ABL by mutation within its last exon.

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7 January 2021

Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell lines

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7 January 2021

Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway

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7 January 2021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

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7 January 2021

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

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7 January 2021

The molecular genetics of Philadelphia chromosome-positive leukemias

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7 January 2021

Chronic myelogenous leukemia: a review

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7 January 2021

Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function

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7 January 2021

Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia

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7 January 2021

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells

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7 January 2021

CML: mechanisms of disease initiation and progression

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7 January 2021

Further evidence for the lack of correlation between the breakpoint site within M-BCR and CML prognosis and for the occasional involvement of p53 in transformation

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P53 tumor suppressor gene in chronic myelogenous leukemia: a sequential study

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7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

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7 January 2021

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

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7 January 2021

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

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7 January 2021

Proteins regulating Ras and its relatives

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7 January 2021

Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family

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7 January 2021

Bcr encodes a GTPase-activating protein for p21rac

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7 January 2021

Increased neutrophil respiratory burst in bcr-null mutants

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7 January 2021

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

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7 January 2021

Signal transduction pathways involved in BCR-ABL transformation

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7 January 2021

CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells

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7 January 2021

Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway

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7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

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7 January 2021

Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth

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7 January 2021

Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL

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7 January 2021

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

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7 January 2021

Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

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7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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7 January 2021

SH2/SH3 signaling proteins

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7 January 2021

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7 January 2021

Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation

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7 January 2021

Transcriptional regulation by extracellular signals: mechanisms and specificity

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7 January 2021

MAPKs: new JNK expands the group

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7 January 2021

The MAPK signaling cascade

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Parallel signal processing among mammalian MAPKs

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7 January 2021

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

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7 January 2021

The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

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7 January 2021

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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7 January 2021

A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.

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7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

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7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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7 January 2021

Phosphoinositide kinases

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7 January 2021

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants

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7 January 2021

CD34+ cell expansion and expression of lineage markers during liquid culture of human progenitor cells

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7 January 2021

Haemopoietic colony-forming cells from peripheral blood stem cell harvests: cytokine requirements and lineage potential

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7 January 2021

Jaks and Stats in signaling by the cytokine receptor superfamily

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7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

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7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

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7 January 2021

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

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7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

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7 January 2021

Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl

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7 January 2021

Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases

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7 January 2021

Cloning the differences between two complex genomes

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7 January 2021

The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc

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7 January 2021

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome

1 reference

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7 January 2021

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

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7 January 2021

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells

1 reference

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7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

1 reference

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7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

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7 January 2021

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

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7 January 2021

bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

1 reference

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7 January 2021

Acute leukaemia in bcr/abl transgenic mice

1 reference

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7 January 2021

SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence

1 reference

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7 January 2021

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

1 reference

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7 January 2021

The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event

1 reference

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7 January 2021

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

1 reference

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7 January 2021

Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene

1 reference

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7 January 2021

Dominant negative MYC blocks transformation by ABL oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900023-1

7 January 2021

Differential complementation of Bcr-Abl point mutants with c-Myc

1 reference

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7 January 2021

Signaling by ABL oncogenes through cyclin D1.

1 reference

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7 January 2021

Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis

1 reference

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7 January 2021

Regulation of the Fas apoptotic cell death pathway by Abl.

1 reference

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7 January 2021

Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.

1 reference

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7 January 2021

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2897%2900023-1

7 January 2021

10.1016/S0304-419X(97)00023-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9426204%20AND%20SRC:MED&resulttype=core&format=json

release_zhbr2w7pp5hajgtyc67lphlt6a

8 November 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zhbr2w7pp5hajgtyc67lphlt6a

24 November 2022

mapped directly with Wikidata item

1 reference