(Q41666761)

6 October 2017

title

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites (English)

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6 October 2017

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Han JW

1

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6 October 2017

Pearson RB

series ordinal

2

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6 October 2017

Dennis PB

series ordinal

3

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6 October 2017

Thomas G

series ordinal

4

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6 October 2017

language of work or name

English

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publication date

1 September 1995

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Journal of Biological Chemistry

6 October 2017

published in

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6 October 2017

volume

270

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6 October 2017

issue

36

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6 October 2017

page(s)

21396-21403

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S6 phosphorylation and the p70s6k/p85s6k

6 October 2017

cites work

1 reference

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MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

21 January 2018

1 reference

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Activation of p70/p85 S6 kinase by a pathway independent of p21ras

21 January 2018

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The molecular basis of retinotectal topography

21 January 2018

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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

21 January 2018

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Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

21 January 2018

1 reference

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Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

21 January 2018

1 reference

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

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Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

21 January 2018

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Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis

21 January 2018

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Regulation of 40S ribosomal protein S6 phosphorylation in Swiss mouse 3T3 cells

21 January 2018

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Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

21 January 2018

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A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation

21 January 2018

1 reference

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Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase

21 January 2018

1 reference

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Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

21 January 2018

1 reference

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Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction

21 January 2018

1 reference

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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

21 January 2018

1 reference

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

1 reference

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1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases

21 January 2018

1 reference

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Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

21 January 2018

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Inhibition of cyclin-dependent kinases by purine analogues

21 January 2018

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Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

21 January 2018

1 reference

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MAP kinase by any other name smells just as sweet

21 January 2018

1 reference

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

21 January 2018

1 reference

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

21 January 2018

1 reference

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Elongation factor-1 alpha gene determines susceptibility to transformation

21 January 2018

1 reference

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Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.36.21396

p70s6k function is essential for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.36.21396

The pathway to signal achievement

21 January 2018

1 reference

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.36.21396

21 January 2018

Identifiers

DOI

10.1074/JBC.270.36.21396

1 reference

6 October 2017

1 reference