(Q41532796)

English

Interaction of heat-shock protein 70 with p53 translated in vitro: evidence for interaction with dimeric p53 and for a role in the regulation of p53 conformation

scientific article published on October 1, 1992

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scholarly article

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Europe PubMed Central

PMC publication ID

2 October 2017

Interaction of heat-shock protein 70 with p53 translated in vitro: evidence for interaction with dimeric p53 and for a role in the regulation of p53 conformation (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

protein biosynthesis

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

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P. Hainaut

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

author name string

J. Milner

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

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1 October 1992

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Europe PubMed Central

PMC publication ID

2 October 2017

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1396554/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1396554/?tool=EBI

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

https://europepmc.org/articles/PMC556809

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

https://europepmc.org/articles/PMC556809?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1396554

22 September 2022

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

11

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

3513-3520

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Monoclonal antibodies specific for simian virus 40 tumor antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

A new anti-p53 monoclonal antibody, previously reported to be directed against the large T antigen of simian virus 40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Oligomerization of oncoprotein p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Molecular basis for heterogeneity of the human p53 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Wild-type p53 can inhibit oncogene-mediated focus formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Evidence that immunological variants of p53 represent alternative protein conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Monoclonal antibody analysis of p53 expression in normal and transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Precise epitope mapping of the murine transformation-associated protein, p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Addition of fresh medium induces cell cycle and conformation changes in p53, a tumour suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

The p53 nuclear localisation signal is structurally linked to a p34cdc2 kinase motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Evidence for allosteric variants of wild-type p53, a tumour suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

The p53 tumour suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

p53 mutations in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Protein folding in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Constitutive expression of p53 protein in enriched normal human marrow blast cell populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

TP53 tumor suppressor gene: a model for investigating human mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=556809

6 June 2018

Tumor suppressor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1396554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/1396554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1396554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conformation hypothesis for the suppressor and promoter functions ofp53in cell growth control and in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/1396554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1396554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1992.TB05434.X

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1396554

22 September 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

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